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To compare the efficacy of bethanechol in the treatment of gastroesophageal reflux with that of antiacids, a prospective, cross-over study was undertaken, in which 20 affected infants and children were randomized into two groups on 6-week alternate bethanechol and antiacids oral medication. Patients were evaluated clinically and by esophageal pH-metry before and after each treatment. Clinical score amelioration was achieved earlier than reflux number reduction and with similar incidence in both groups of patients, irrespectively to the initial medication; moreover, the differences in the degree of improvement between the two groups after either treatment were not found to be significant. These results fail to show that bethanechol is more effective than antiacids in controlling gastroesophageal reflux; moreover, bethanechol is more difficult to administer and offers a higher rate of undesired side effects.
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
August 1983,
The Journal of pediatrics,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
February 1980,
The Journal of pediatrics,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
November 1984,
The American review of respiratory disease,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
March 1977,
The American journal of digestive diseases,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
January 1984,
The Journal of pediatrics,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
October 1982,
ZFA. Zeitschrift fur Allgemeinmedizin,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
January 1986,
Journal of pediatric gastroenterology and nutrition,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
November 1997,
The American journal of gastroenterology,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
January 1986,
Journal of pediatric gastroenterology and nutrition,
P Levi, and
F Marmo, and
C Saluzzo, and
D Dell'Olio, and
N Ansaldi, and
L Giuliani, and
O Guardamagna, and
M Mostert, and
A Ponzone
November 2001,
Journal of gastroenterology and hepatology,
