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The protective efficacy of oral B subunit killed whole-cell (BS-WC) and killed whole-cell (WC) cholera vaccines was assessed in 63 498 Bangladeshi children aged 2-15 years and women aged over 15 years. Each received three doses of BS-WC, WC, or placebo in a randomised, double-blinded fashion. Surveillance for cases seeking medical care up to six months after the third dose revealed 26 cases of confirmed cholera in the placebo group, 4 cases in the BS-WC group (protective efficacy 85%; p less than 0.0001), and 11 cases in the WC group (protective efficacy 58%; p less than 0.01). For each vaccine protective efficacy was consistent in different age-groups (2-10 years versus greater than 10 years) and for different severities of cholera.
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
January 2020,
PloS one,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
May 2019,
International health,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
April 1997,
Lancet (London, England),
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
September 1986,
Lancet (London, England),
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
January 2022,
Vaccine,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
March 2023,
Vaccine,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
January 1967,
Bulletin of the World Health Organization,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
June 2011,
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America,
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
August 1990,
Lancet (London, England),
J D Clemens, and
D A Sack, and
J R Harris, and
J Chakraborty, and
M R Khan, and
B F Stanton, and
B A Kay, and
M U Khan, and
M Yunus, and
W Atkinson
January 2024,
The Cochrane database of systematic reviews,
