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The responses of the noradrenaline (NA)- and adrenaline (A)-containing neurons to a reserpine treatment have been studied in the rat brain by using biochemical indices of the neuronal activity. Three days after multiple reserpine injections, tyrosine hydroxylase activity was significantly increased in the locus coeruleus (LC), A1-C1 and C2 regions. No change in this activity was observed in the A2 region. Furthermore, the NA and A endogenous levels were markedly reduced both in NA and A cell bodies and/or terminals, suggesting a reserpine action on NA and A neurons. The NA turnover was unchanged in all the regions analyzed. Conversely, the A turnover was reduced in the LC, A2 and C2 regions and in the nucleus periventricularis of the hypothalamus. This result suggests a different degree of sensitivity and/or response of the NA and A neurons following reserpine administration.
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
September 1983,
European journal of pharmacology,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
October 1971,
British journal of pharmacology,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
February 1958,
Pharmaceutisch weekblad,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
December 1986,
Stomatologie der DDR,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
January 1958,
Journal of neurochemistry,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
May 1967,
Activitas nervosa superior,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
July 1998,
Physiology & behavior,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
January 1981,
Annales de l'anesthesiologie francaise,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
October 1959,
Journal of neurochemistry,
L Lambás-Seńas, and
G Chamba, and
R Fety, and
B Renaud
September 1948,
British journal of pharmacology and chemotherapy,
