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Adrenal catecholamine concentration was measured by HPLC with electrochemical detection in male rats after ten days of bromocriptine and haloperidol (0.05, 0.5 and 5.0 mg kg-1) and vehicle (1.0 ml kg-1) treatments subcutaneously. There were four rats in each group. The results indicate that bromocriptine treatment significantly increased dopamine (DA), noradrenaline (NA) and adrenaline (A) content in a dose-dependent manner. The NA/DA ratio was unchanged, but the A/NA ratio was significantly increased after treatments with two higher doses of the drug. Haloperidol treatment, on the other hand, had no significant effect on dopamine and a biphasic effect on adrenaline content. Noradrenaline concentration increased only after the lowest dose of the drug. There was no significant change in NA/DA or A/NA ratios in any group. The dopamine metabolite, dihydroxyphenylacetic acid (DOPAC), was not detected in any adrenal gland.
S N Baksi, and
M J Hughes, and
H K Strahlendorf
October 1987,
Clinical neuropharmacology,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
October 1982,
Acta endocrinologica,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
April 1974,
Experientia,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
September 1983,
The Journal of pharmacology and experimental therapeutics,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
November 1982,
North Carolina medical journal,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
April 2015,
Journal of neurotrauma,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
January 1984,
Biomedica biochimica acta,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
August 1980,
European journal of clinical pharmacology,
S N Baksi, and
M J Hughes, and
H K Strahlendorf
April 1989,
Presse medicale (Paris, France : 1983),
S N Baksi, and
M J Hughes, and
H K Strahlendorf
January 1977,
Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung,
