BIOMAT Database Logo BIOMAT Database Logo

In vitro Antimicrobial Activities and Mechanism of 1-Octen-3-ol against Food-related Bacteria and Pathogenic Fungi. 2017

Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
College of Life Science, Sichuan University.

1-Octen-3-ol, known as mushroom alcohol, is a natural product extracted from fungi and plants. Its antimicrobial activities against five common food-related bacteria and two pathogenic fungi were evaluated in this paper, including Staphylococcus aureus, Bacillus subtilis, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Fusarium tricinctum and Fusarium oxysporum. The results showed that 1-octen-3-ol had a strong antibacterial activity against the tested bacteria, especially against Gram-positive bacteria, and it can also inhibit fungal growth and spore germination. The minimum inhibitory concentrations (MICs) for Gram-positive bacteria and Gram-negative bacteria were 1.0 and 2.0 mg/mL, respectively. The minimum bactericidal concentrations (MBCs) for Gram-positive bacteria and Gram-negative bacteria were 4.0 and 8.0 mg/mL, respectively. The completely inhibitory concentrations for fungal growth and spore germination were 8.0 and 2.0 mg/ml, respectively. Cell constituents' leakage and scanning electron microscope assays indicated that 1-octen-3-ol changed the permeability of the cell membrane. Discrepant antimicrobial activity between 1-octen-3-ol and 1-octen-3-one indicated that hydroxyl may play a decisive role in antimicrobial activity. It is suggested that 1-octen-3-ol, with attractive mushroom aroma and antimicrobial activity, has potential applications in control of pathogens.

UI MeSH Term Description Entries
D011550 Pseudomonas aeruginosa A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection. Bacillus aeruginosus,Bacillus pyocyaneus,Bacterium aeruginosum,Bacterium pyocyaneum,Micrococcus pyocyaneus,Pseudomonas polycolor,Pseudomonas pyocyanea
D004305 Dose-Response Relationship, Drug The relationship between the dose of an administered drug and the response of the organism to the drug. Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D005516 Food Microbiology The presence of bacteria, viruses, and fungi in food and food products. This term is not restricted to pathogenic organisms: the presence of various non-pathogenic bacteria and fungi in cheeses and wines, for example, is included in this concept. Microbiology, Food
D005670 Fusarium A mitosporic Hypocreales fungal genus, various species of which are important parasitic pathogens of plants and a variety of vertebrates. Teleomorphs include GIBBERELLA. Fusariums
D000442 Octanols Isomeric forms and derivatives of octanol (C8H17OH). Alcohols, Octyl,Heptylcarbinols,Hydroxyoctanes,Octylic Alcohols,Alcohols, Octylic,Octyl Alcohols
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D000935 Antifungal Agents Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics
D001412 Bacillus subtilis A species of gram-positive bacteria that is a common soil and water saprophyte. Natto Bacteria,Bacillus subtilis (natto),Bacillus subtilis subsp. natto,Bacillus subtilis var. natto
D013211 Staphylococcus aureus Potentially pathogenic bacteria found in nasal membranes, skin, hair follicles, and perineum of warm-blooded animals. They may cause a wide range of infections and intoxications.

Related Publications

Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
Antimicrobial activities of Tephrosia vogelii against selected pathogenic fungi and bacteria strains.
January 2020, Mycology,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi.
January 2015, Frontiers in cellular and infection microbiology,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
1-Octen-3-ol - the attractant that repels.
January 2015, F1000Research,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
[Contribution on the occurrence of 1-octen-3-ol].
April 1968, European journal of biochemistry,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
In vitro antibacterial activities and mechanism of sugar fatty acid esters against five food-related bacteria.
November 2015, Food chemistry,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
Evaluation of In-vitro Antimicrobial Potential of Daphne retusa Hemsl. Against Human Pathogenic Bacteria and Fungi.
January 2018, Current topics in medicinal chemistry,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
Antimicrobial activity of Novel spinel nanoferrites against pathogenic fungi and bacteria.
January 2020, World journal of microbiology & biotechnology,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
ANTIMICROBIAL ACTIVITY OF Echinops kebericho AGAINST HUMAN PATHOGENIC BACTERIA AND FUNGI.
January 2016, African journal of traditional, complementary, and alternative medicines : AJTCAM,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
Carbon dioxide and 1-octen-3-ol as mosquito attractants.
September 1989, Journal of the American Mosquito Control Association,
Chuan Xiong, and Qiang Li, and Shuhong Li, and Cheng Chen, and Zuqin Chen, and Wenli Huang
[In vitro activities of Odorrana grahami antimicrobial peptides from skin against 5 pathogenic bacteria].
December 2009, Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials,
Copied contents to your clipboard!