Patient treatment preferences for symptomatic refractory urodynamic idiopathic detrusor overactivity. 2017

Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
Department of Urology, University College London Hospital, London, W1G 8PH, UK.

BACKGROUND There is a multiplicity of treatments currently available for patients with symptomatic refractory urodynamic idiopathic detrusor overactivity (SRU IDO). We have assessed patient treatment preferences and their outcomes over a 12-month period from January 1 2009 to December 31 2009. METHODS A retrospective database of all patients with SRU IDO was reviewed for patient demographics, treatment preference, and outcome. All patients attending for treatment in the time period were offered: no further treatment, repeat bladder training ± antimuscarinic (BT ± AM), acupuncture, intravesical botulinum toxin injection, sacral neuromodulation (SNM), clam cystoplasty ± Mitrofanoff channel formation, and ileal conduit. METHODS Statistical analysis of outcomes was done by Chi-square test, and statistical significance was determined as P < 0.05. RESULTS A total of 217 patients with SRU IDO underwent primary treatment in this time period, with a median age of 56 years and follow-up for a minimum of 12 months' posttreatment to determine outcome. No patients opted for any further treatment or an ileal conduit. The majority of patients opted for intravesical botulinum toxin injections and SNM with similar success rates (approximately 70%). A small number of patients decided to have nonsurgical interventions (BT ± AM or acupuncture) and had a broadly similar success rate (50%). A minority opted for clam cystoplasty ± Mitrofanoff channel formation - this group reported the highest success rate at 86%. CONCLUSIONS Treatment options in SRU IDO are diverse, with the majority of patients opting for minimally invasive surgery. Clinicians should be familiar with all treatment options for management of SRU IDO.

UI MeSH Term Description Entries

Related Publications

Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
January 2007, International urology and nephrology,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
May 2006, Urology,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
January 2022, Urology,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
December 2006, International journal of clinical practice. Supplement,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
June 2017, Neurourology and urodynamics,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
July 2005, Urology,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
June 2007, International urogynecology journal and pelvic floor dysfunction,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
January 2019, Urology,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
September 2010, Annals of the Academy of Medicine, Singapore,
Christina L Fontaine, and Ian Rudd, and Mahreen Pakzad, and Rizwan Hamid, and Jeremy L Ockrim, and Tamsin J Greenwell
February 2020, Neurourology and urodynamics,
Copied contents to your clipboard!