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The lipoprotein fractions in mesenteric lymph were monitored following intraduodenal administration of arachis oil and oleic, linoleic and linolenic fatty acids to rats. An increase in the chylomicron fraction, but not the VLDL or LDL fraction, was observed with each lipid. The greater the degree of unsaturation of the fatty acid, the more rapid the onset of chylomicron synthesis. The administration of linoleic acid and arachis oil produced the highest concentration of chylomicrons in the lymph. These results reflect differences in the rate of absorption and biochemical metabolism of the lipids and have implications for the selection of vehicles for the delivery of drugs by the lymphatic route.
M Cheema, and
K J Palin, and
S S Davis
October 1988,
Pharmaceutical research,
M Cheema, and
K J Palin, and
S S Davis
October 1988,
Pharmaceutical research,
M Cheema, and
K J Palin, and
S S Davis
August 2011,
Molecular pharmaceutics,
M Cheema, and
K J Palin, and
S S Davis
November 2015,
EMBO molecular medicine,
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K J Palin, and
S S Davis
February 2021,
Pharmaceutics,
M Cheema, and
K J Palin, and
S S Davis
October 2019,
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K J Palin, and
S S Davis
December 2021,
Advanced materials (Deerfield Beach, Fla.),
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K J Palin, and
S S Davis
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American journal of physiology. Endocrinology and metabolism,
M Cheema, and
K J Palin, and
S S Davis
June 2002,
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,
M Cheema, and
K J Palin, and
S S Davis
September 2011,
Advanced drug delivery reviews,
