Lysozyme activity in saliva from children with various degree of gingivitis. 1979

T Modéer, and S Twetman

The lysozyme activity was determined in paraffin stimulated whole saliva from 51 randomly selected children. The average age was 6.5 years. The children were divided into four groups according to their degree of gingival inflammation. An agardiffusion method was used with Micrococcus lysodeikticus as indicator of the lysozyme activity. The mean value of the lysozyme activity was determined to 48.4 microgram/ml. In the non-inflamed group the enzyme activity was 8.7 microgram/ml, whereas it was lower, 31.5 microgram/ml, in children with inflamed gingiva. The correlation coefficient (p less than 0.05) suggest that there is a negative relationship between saliva lysozyme and the degree of gingival inflammation. Furthermore this study indicates that lysozyme acts as one of the resistant-factors against gingival inflammation in young individuals.

UI MeSH Term Description Entries
D008297 Male Males
D009113 Muramidase A basic enzyme that is present in saliva, tears, egg white, and many animal fluids. It functions as an antibacterial agent. The enzyme catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. EC 3.2.1.17. Lysozyme,Leftose,N-Acetylmuramide Glycanhydrolase,Glycanhydrolase, N-Acetylmuramide,N Acetylmuramide Glycanhydrolase
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D005891 Gingivitis Inflammation of gum tissue (GINGIVA) without loss of connective tissue. Gingivitides
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012463 Saliva The clear, viscous fluid secreted by the SALIVARY GLANDS and mucous glands of the mouth. It contains MUCINS, water, organic salts, and ptylin. Salivas

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