BIOMAT Database Logo BIOMAT Database Logo

Apomorphine infusion for motor fluctuations in Parkinson's disease. 1987

J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage

UI MeSH Term Description Entries
D007263 Infusions, Parenteral The administration of liquid medication, nutrient, or other fluid through some other route than the alimentary canal, usually over minutes or hours, either by gravity flow or often by infusion pumping. Intra-Abdominal Infusions,Intraperitoneal Infusions,Parenteral Infusions,Peritoneal Infusions,Infusion, Intra-Abdominal,Infusion, Intraperitoneal,Infusion, Parenteral,Infusion, Peritoneal,Infusions, Intra-Abdominal,Infusions, Intraperitoneal,Infusions, Peritoneal,Intra Abdominal Infusions,Intra-Abdominal Infusion,Intraperitoneal Infusion,Parenteral Infusion,Peritoneal Infusion
D007980 Levodopa The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. L-Dopa,3-Hydroxy-L-tyrosine,Dopaflex,Dopar,L-3,4-Dihydroxyphenylalanine,Larodopa,Levopa,3 Hydroxy L tyrosine,L 3,4 Dihydroxyphenylalanine,L Dopa
D010300 Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary
D004359 Drug Therapy, Combination Therapy with two or more separate preparations given for a combined effect. Combination Chemotherapy,Polychemotherapy,Chemotherapy, Combination,Combination Drug Therapy,Drug Polytherapy,Therapy, Combination Drug,Chemotherapies, Combination,Combination Chemotherapies,Combination Drug Therapies,Drug Polytherapies,Drug Therapies, Combination,Polychemotherapies,Polytherapies, Drug,Polytherapy, Drug,Therapies, Combination Drug
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001058 Apomorphine A derivative of morphine that is a dopamine D2 agonist. It is a powerful emetic and has been used for that effect in acute poisoning. It has also been used in the diagnosis and treatment of parkinsonism, but its adverse effects limit its use. Apokinon,Apomorphin-Teclapharm,Apomorphine Chloride,Apomorphine Hydrochloride,Apomorphine Hydrochloride Anhydrous,Apomorphine Hydrochloride, Anhydrous,Apomorphine Hydrochloride, Hemihydrate,Britaject,Apomorphin Teclapharm

Related Publications

J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Apomorphine for motor fluctuations and freezing in Parkinson's disease.
March 1995, The Annals of pharmacotherapy,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Controlled-release transdermal apomorphine treatment for motor fluctuations in Parkinson's disease.
September 2002, Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
[Subcutaneous administration of apomorphine in motor fluctuations in Parkinson's disease].
January 1990, Revue neurologique,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Apomorphine and levodopa infusion for motor fluctuations and dyskinesia in advanced Parkinson disease.
August 2018, Journal of neural transmission (Vienna, Austria : 1996),
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
[Duodenale levodopa and apomorphine infusion for motor complications in advanced Parkinson's disease].
September 2018, Fortschritte der Neurologie-Psychiatrie,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Improvements in non-motor and motor fluctuations in parkinson's disease after intermittent apomorphine treatment.
January 2017, Neurology India,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
[Apomorphine: an alternative in the control of motor fluctuations in Parkinson's disease].
June 1995, Arquivos de neuro-psiquiatria,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Efficacy of long-term continuous subcutaneous apomorphine infusion in advanced Parkinson's disease with motor fluctuations: a multicenter study.
June 2008, Movement disorders : official journal of the Movement Disorder Society,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
[Treatment of motor fluctuations in Parkinson's disease with subcutaneous injections of apomorphine].
January 1995, Medicina,
J A Obeso, and F Grandas, and J Vaamonde, and M Rosario Luguin, and J M Martínez-Lage
Sublingual apomorphine in the treatment of Parkinson's disease complicated by motor fluctuations.
December 1991, Clinical neuropharmacology,
Copied contents to your clipboard!