Transmucosal fentanyl for severe cancer pain: Nasal mucosa superior to oral mucosa? 2016

Harald Breivik
University of Oslo, Faculty of Medicine, Oslo, Norway; Department of Pain Management and Research, Oslo University Hospital, Oslo, Norway; Department of Anaesthesiology, Oslo University Hospital, Oslo, Norway. Electronic address: harald.breivik@medsin.uio.no.

UI MeSH Term Description Entries
D009061 Mouth Mucosa Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations. Buccal Mucosa,Oral Mucosa,Mucosa, Mouth,Mucosa, Oral
D009297 Nasal Mucosa The mucous lining of the NASAL CAVITY, including lining of the nostril (vestibule) and the OLFACTORY MUCOSA. Nasal mucosa consists of ciliated cells, GOBLET CELLS, brush cells, small granule cells, basal cells (STEM CELLS) and glands containing both mucous and serous cells. Nasal Epithelium,Schneiderian Membrane,Epithelium, Nasal,Membrane, Schneiderian,Mucosa, Nasal
D005283 Fentanyl A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078) Phentanyl,Duragesic,Durogesic,Fentanest,Fentanyl Citrate,Fentora,R-4263,Sublimaze,Transmucosal Oral Fentanyl Citrate,R 4263,R4263
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072716 Cancer Pain Pain that may be caused by or related to cellular, tissue, and systemic changes that occur during NEOPLASM growth, tissue invasion, and METASTASIS. Cancer-Associated Pain,Cancer-Related Pain,Neoplasm-Associated Pain,Neoplasm-Related Pain,Oncological Pain,Oncology Pain,Tumor-Associated Pain,Tumor-Related Pain,Cancer Associated Pain,Cancer Pains,Cancer Related Pain,Cancer-Associated Pains,Cancer-Related Pains,Neoplasm Associated Pain,Neoplasm Related Pain,Neoplasm-Associated Pains,Neoplasm-Related Pains,Oncological Pains,Oncology Pains,Pain, Cancer,Pain, Cancer-Associated,Pain, Cancer-Related,Pain, Neoplasm-Associated,Pain, Neoplasm-Related,Pain, Oncological,Pain, Oncology,Pain, Tumor-Associated,Pain, Tumor-Related,Pains, Cancer,Pains, Cancer-Associated,Pains, Cancer-Related,Pains, Neoplasm-Associated,Pains, Neoplasm-Related,Pains, Oncological,Pains, Oncology,Pains, Tumor-Associated,Pains, Tumor-Related,Tumor Associated Pain,Tumor Related Pain,Tumor-Associated Pains,Tumor-Related Pains
D059390 Breakthrough Pain Acute pain that comes on rapidly despite the use of pain medication. Pain, Breakthrough,Breakthrough Pains,Pains, Breakthrough

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