Biomaterial Database

Radiologically isolated syndrome should be treated with disease-modifying therapy - No. 2017

Andrés Labiano-Fontcuberta, and Julián Benito-León

Department of Neurology, Hospital Universitario 12 de Octubre, Madrid, Spain.

UI	MeSH Term	Description	Entries
D007155	Immunologic Factors	Biologically active substances whose activities affect or play a role in the functioning of the immune system.	Biological Response Modifier,Biomodulator,Immune Factor,Immunological Factor,Immunomodulator,Immunomodulators,Biological Response Modifiers,Biomodulators,Factors, Immunologic,Immune Factors,Immunological Factors,Modifiers, Biological Response,Response Modifiers, Biological,Factor, Immune,Factor, Immunological,Factors, Immune,Factors, Immunological,Modifier, Biological Response,Response Modifier, Biological
D008279	Magnetic Resonance Imaging	Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.	Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D009103	Multiple Sclerosis	An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)	MS (Multiple Sclerosis),Multiple Sclerosis, Acute Fulminating,Sclerosis, Disseminated,Disseminated Sclerosis,Sclerosis, Multiple
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D061345	Early Medical Intervention	Action taken to reduce susceptibility or exposure to health problems and to detect and treat disease in early stages.	Early Medical Interventions,Intervention, Early Medical,Interventions, Early Medical,Medical Intervention, Early,Medical Interventions, Early
D020278	Demyelinating Autoimmune Diseases, CNS	Conditions characterized by loss or dysfunction of myelin (see MYELIN SHEATH) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or OLIGODENDROGLIA associated autoantigens.	Autoimmune Demyelinating Diseases, Central Nervous System,Spinal Cord Demyelinating Autoimmune Diseases,Autoimmune Demyelinating Diseases, CNS,Autoimmune Demyelinating Diseases, Cerebral,Autoimmune Demyelinating Diseases, Spinal Cord,Autoimmune Demyelinating Disorders, CNS,Autoimmune Diseases, Demyelinating, Brain,Brain Autoimmune Demyelinating Diseases,CNS Autoimmune Demyelinating Disorders,CNS Demyelinating Autoimmune Diseases,Cerebral Demyelinating Diseases, Autoimmune,Demyelinating Autoimmune Diseases, Brain,Demyelinating Autoimmune Diseases, Central Nervous System,Demyelinating Autoimmune Diseases, Cerebral,Demyelinating Autoimmune Diseases, Spinal Cord,Demyelinating Autoimmune Disorders, CNS,Demyelinating Disease, Autoimmune, CNS