To analyze the alterations in corneal topography and keratometry (K) after glued transscleral-fixated intraocular lens (IOL) implantation. Dr. Agarwal's Eye Hospital, Chennai, India. Prospective case series. Eyes having glued IOL implantation for aphakia or subluxated lens (>180 degrees) were included. Preoperative autorefractometer and corneal topography was performed. Intraoperative parameters, namely the type, position, and incision size, flap position, and number of sutures were noted. The mean corneal curvature in a steep meridian (maximum K), flat meridian (minimum K), simulated K, pachymetry, and surgically induced astigmatism (SIA) were analyzed. This study evaluated 16 eyes with aphakia and 15 eyes with a subluxated over a mean follow-up of 12 months ± 6 (SD). There was a significant reduction in mean simulated K (P = .014) after surgery. The maximum K decreased significantly (P = .002), from 44.85 ± 2.83 diopters (D) preoperatively to 44.47 ± 2.75 D at 6 months. The mean SIA was 1.0 ± 0.7 D (range 0.16 to 3.6 D) and the postoperative astigmatism analysis by the Alpins method was negative (-1.8), showing relative flattening after surgery. Multiple regression analysis found no association between postoperative vision and preoperative maximum K, postoperative simulated K, incision size, and number of sutures. There was no correlation between the postoperative simulated K and incision position (P = .674), sutures (P = .881), and scleral flap position (P = .401). Glued transscleral fixation resulted in a reduction in mean corneal curvature in the steep meridian and there was significant change in corneal astigmatism.