Biomaterial Database

Penicillamine in the therapy of hereditary muscular dystrophy in chickens. 1979

J H Milhorat, and A T Milhorat

This was a brief 6-month study of the possible value of penicillamine in adult chickens with hereditary muscular dystrophy. Detailed histologic investigation of various parameters of muscle architecture yielded no evidence of significant therapeutic effect. Several serious toxic symptoms were noted. It is suggested that in muscular dystrophy, a disease in which the main feature is profound alteration of muscle structure, histologic studies may be the best means of documenting response to therapeutic agents.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009137	Muscular Dystrophy, Animal	MUSCULAR DYSTROPHY that occurs in VERTEBRATE animals.	Animal Muscular Dystrophies,Animal Muscular Dystrophy,Dystrophies, Animal Muscular,Dystrophy, Animal Muscular,Muscular Dystrophies, Animal
D010396	Penicillamine	3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.	Dimethylcysteine,Mercaptovaline,beta,beta-Dimethylcysteine,Copper Penicillaminate,Cuprenil,Cuprimine,D-3-Mercaptovaline,D-Penicillamine,Metalcaptase,D 3 Mercaptovaline,D Penicillamine,Penicillaminate, Copper,beta,beta Dimethylcysteine
D011187	Posture	The position or physical attitude of the body.	Postures
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia