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Hepatomegaly and elevated liver enzymes in patients with diabetes are commonly associated with fatty liver disease. However, physicians often forget about another intrinsic substance that can cause a similar clinical picture-glycogen. Liver stores approximately one third of the total body glycogen and is responsible for blood glucose homeostasis. Excessive hepatocellular glycogen accumulation occurs not only in congenital glycogen storage diseases, but also in acquired conditions associated with hyperglycemic-hyperinsulinemic states such as uncontrolled diabetes mellitus, high-dose corticosteroid use, and dumping syndrome. All reported cases of acquired abnormal glycogen deposition described a diffuse form of hepatic glycogenosis with the entire liver involved in the accumulating process. To our knowledge, this is the first reported case of abnormal focal glycogen deposition in a patient with diabetes mellitus type 1 with imaging and pathologic correlation. Awareness of the imaging appearance of focal glycogen deposition can help to distinguish it from other pathologic conditions.
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
January 2011,
Revista clinica espanola,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
June 2015,
Korean journal of pediatrics,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
January 2008,
Journal of diabetes and its complications,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
December 2014,
World journal of diabetes,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
September 2005,
Medicina clinica,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
October 2000,
Journal of paediatrics and child health,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
February 1997,
International journal of oncology,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
June 2003,
Diabetes, nutrition & metabolism,
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
April 2018,
Internal medicine (Tokyo, Japan),
Tetiana Glushko, and
Sergiy V Kushchayev, and
Dmitry Trifanov, and
Aliaksei Salei, and
Diego Morales, and
Gerard Berry, and
Justin Mackey, and
Oleg M Teytelboym
March 2007,
Diabetic medicine : a journal of the British Diabetic Association,
