Biomaterial Database

Bile acids from the harp seals, Phoca groenlandica. 1988

J Hellou, and A King, and I H Ni

Science Branch, Department of Fisheries and Oceans, St. John's, Newfoundland, Canada.

1. The bile acids composition of the harp seal, Phoca groenlandica, collected around Newfoundland, Canada, had been examined. 2. 13C n.m.r. spectroscopy of the crude bile extract was superior to t.l.c. analysis in revealing the presence of phocaecholic acid and a taurine moiety in this mixture. 3. The relative percentage of cholic, phocaecholic and chenodeoxycholic acids was 60.5% (+/- 4.5), 21.4% (+/- 4.0) and 18.1% (+/- 5.8), respectively. 4. The variation in the percentage of bile acids did not correlate with the sex of the sampled animals, but varied significantly with the age of the seals.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009682	Magnetic Resonance Spectroscopy	Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).	In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D010872	Caniformia	Suborder of dog-like carnivores which include dogs, coyotes, skunks, mustelids, walruses, seals, bears, and procyonids.	Pinnipedia,Pinnipeds
D002635	Chenodeoxycholic Acid	A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.	Chenic Acid,Chenodeoxycholate,Chenodiol,Gallodesoxycholic Acid,Chenique Acid,Chenix,Chenofalk,Chenophalk,Henohol,Quenobilan,Quenocol,Sodium Chenodeoxycholate,Acid, Chenic,Acid, Chenique,Acid, Chenodeoxycholic,Acid, Gallodesoxycholic,Chenodeoxycholate, Sodium
D002793	Cholic Acids	The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.	Cholalic Acids,Acids, Cholalic,Acids, Cholic
D005260	Female		Females
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001647	Bile Acids and Salts	Steroid acids and salts. The primary bile acids are derived from cholesterol in the liver and usually conjugated with glycine or taurine. The secondary bile acids are further modified by bacteria in the intestine. They play an important role in the digestion and absorption of fat. They have also been used pharmacologically, especially in the treatment of gallstones.	Bile Acid,Bile Salt,Bile Salts,Bile Acids,Acid, Bile,Acids, Bile,Salt, Bile,Salts, Bile
D046048	Seals, Earless	The family Phocidae, suborder PINNIPEDIA, order CARNIVORA, comprising the true seals. They lack external ears and are unable to use their hind flippers to walk. It includes over 18 species including the harp seal, probably the best known seal species in the world.	Halichoerus grypus,Mirounga,Pagophilus groenlandicus,Seal, Elephant,Seal, Harp,Seals, True,Phoca groenlandica,Phocidae,Seal, Gray,Earless Seal,Earless Seals,Elephant Seal,Elephant Seals,Gray Seal,Gray Seals,Harp Seal,Harp Seals,Seal, Earless,Seal, True,Seals, Elephant,Seals, Gray,Seals, Harp,True Seal,True Seals