| D011487 |
Protein Conformation |
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain). |
Conformation, Protein,Conformations, Protein,Protein Conformations |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
|
| D000076122 |
Disks Large Homolog 4 Protein |
A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. |
Discs Large Homolog 4 Protein,PSD-95 Protein,PSD95 Protein,Postsynaptic Density Protein 95,SAP-90 Protein,SAP90 Protein,Synapse-Associated Protein 90,PSD 95 Protein,SAP 90 Protein,Synapse Associated Protein 90 |
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| D000818 |
Animals |
Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. |
Animal,Metazoa,Animalia |
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| D014644 |
Genetic Variation |
Genotypic differences observed among individuals in a population. |
Genetic Diversity,Variation, Genetic,Diversity, Genetic,Diversities, Genetic,Genetic Diversities,Genetic Variations,Variations, Genetic |
|
| D015971 |
Gene Expression Regulation, Enzymologic |
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis. |
Enzymologic Gene Expression Regulation,Regulation of Gene Expression, Enzymologic,Regulation, Gene Expression, Enzymologic |
|
| D051379 |
Mice |
The common name for the genus Mus. |
Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus |
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| D054633 |
Receptor-Like Protein Tyrosine Phosphatases, Class 5 |
A subclass of receptor-like protein tryosine phosphatases that contain an extracellular fibronectin III-like domain along with a carbonic anhydrase-like domain. |
Protein Tyrosine Phosphatase, Receptor Type G,Protein Tyrosine Phosphatase, Receptor Type Z,PTPRG Phosphatase,Phosphacan,Protein Tyrosine Phosphatase, Receptor Type, G,Protein Tyrosine Phosphatase, Receptor-Type Z,Ptprz Phosphatase,RPTP-zeta,RPTPbeta,RPTPgamma,RPTPzeta-beta,Receptor Protein Tyrosine Phosphatase gamma,Receptor Protein Tyrosine Phosphatase zeta-beta,Receptor Protein Tyrosine Phosphatase-beta,Receptor Protein Tyrosine Phosphatase-zeta,Receptor-Like Protein Tyrosine Phosphatases, Class V,Receptor-Type Protein-Tyrosine Phosphatase-beta,Phosphatase, PTPRG,Phosphatase, Ptprz,Phosphatase-beta, Receptor-Type Protein-Tyrosine,Protein-Tyrosine Phosphatase-beta, Receptor-Type,Receptor Like Protein Tyrosine Phosphatases, Class 5,Receptor Like Protein Tyrosine Phosphatases, Class V,Receptor Protein Tyrosine Phosphatase beta,Receptor Protein Tyrosine Phosphatase zeta,Receptor Protein Tyrosine Phosphatase zeta beta,Receptor Type Protein Tyrosine Phosphatase beta |
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| D057809 |
HEK293 Cells |
A cell line generated from human embryonic kidney cells that were transformed with human adenovirus type 5. |
293T Cells,HEK 293 Cell Line,HEK 293 Cells,Human Embryonic Kidney Cell Line 293,Human Kidney Cell Line 293,293 Cell, HEK,293 Cells, HEK,293T Cell,Cell, 293T,Cell, HEK 293,Cell, HEK293,Cells, 293T,Cells, HEK 293,Cells, HEK293,HEK 293 Cell,HEK293 Cell |
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| D018345 |
Mice, Knockout |
Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes. |
Knockout Mice,Mice, Knock-out,Mouse, Knockout,Knock-out Mice,Knockout Mouse,Mice, Knock out |
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