-transparent.png){kind=logo}
The 2-(3-fluoro-4-hydroxyphenyl)ethylamine and its N,N-dialkyl derivatives were synthesized. The affinity of new compounds for dopamine binding sites was measured in a test involving displacement of [3H]SCH 23390 (D-1 selective) and [3H]spiperone (D-2 selective) from homogenized rat striatal tissue. No compound proved effective in displacing [3H]SCH 23390. Two derivatives are selective displacers of [3H]spiperone.
Related Publications
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
January 1992,
Drug design and discovery,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
November 1992,
Journal of medicinal chemistry,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
February 1994,
Drug design and discovery,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
June 1996,
Chemical & pharmaceutical bulletin,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
January 1993,
Drug design and discovery,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
January 1999,
Nucleosides & nucleotides,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
December 1997,
Journal of medicinal chemistry,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
September 1990,
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
February 2007,
Yao xue xue bao = Acta pharmaceutica Sinica,
M Cardellini, and
G M Cingolani, and
F Claudi, and
V Perlini, and
W Balduini, and
F Cattabeni
December 1990,
Journal of medicinal chemistry,
