BIOMAT Database Logo BIOMAT Database Logo

Excretion of estrone-3-glucuronide in urine in spontaneous and induced ovulatory cycles. 1988

M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Institute for Research in Reproduction (ICMR), Parel, Bombay, India.

Response of the ovary to ovulation-inducing agents, such as clomiphene citrate and gonadotropin, was assessed using estimations of urinary estrone-3-glucuronide (E1G) by an ELISA test. Baseline data collected over 58 cycles from regularly menstruating women were used as reference. Further, the pattern of E1G excretion was compared with ultrasound assessment of follicular growth. In ovulatory cycles, a good correlation is seen between follicular growth and follicular function. However, when cystic follicles develop after treatment, the correlation is poor: the follicle increases in size without a corresponding increase in E1G excretion. It is suggested that ultrasound examination and hormonal pattern should be used concurrently to assess the response of the ovary to ovulation-inducing agents.

UI MeSH Term Description Entries
D008183 Luteal Phase The period in the MENSTRUAL CYCLE that follows OVULATION, characterized by the development of CORPUS LUTEUM, increase in PROGESTERONE production by the OVARY and secretion by the glandular epithelium of the ENDOMETRIUM. The luteal phase begins with ovulation and ends with the onset of MENSTRUATION. Menstrual Cycle, Luteal Phase,Menstrual Cycle, Secretory Phase,Menstrual Secretory Phase,Postovulatory Phase,Phase, Luteal,Phase, Postovulatory,Secretory Phase, Menstrual
D008596 Menotropins Extracts of urine from menopausal women that contain high concentrations of pituitary gonadotropins, FOLLICLE STIMULATING HORMONE and LUTEINIZING HORMONE. Menotropins are used to treat infertility. The FSH:LH ratio and degree of purity vary in different preparations. Gonadotropins, Human Menopausal,Human Menopausal Gonadotropin,CP-89044,CP-90033,HMG Ferring,HMG Lepori,HMG Massone,Humegon,Menogon,Menopur,Menotrophin,Normegon,ORG-31338,Pergonal,Pergonal-500,CP 89044,CP 90033,CP89044,CP90033,Gonadotropin, Human Menopausal,Human Menopausal Gonadotropins,Lepori, HMG,Menopausal Gonadotropin, Human,ORG 31338,ORG31338,Pergonal 500,Pergonal500
D010060 Ovulation The discharge of an OVUM from a rupturing follicle in the OVARY. Ovulations
D010062 Ovulation Induction Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum. Ovarian Stimulation,Ovarian Stimulations,Stimulation, Ovarian,Stimulations, Ovarian
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002996 Clomiphene A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively. Chloramiphene,Clomifene,Clomid,Clomide,Clomifen,Clomiphene Citrate,Clomiphene Hydrochloride,Clostilbegit,Dyneric,Gravosan,Klostilbegit,Serophene,Citrate, Clomiphene,Hydrochloride, Clomiphene
D004797 Enzyme-Linked Immunosorbent Assay An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. ELISA,Assay, Enzyme-Linked Immunosorbent,Assays, Enzyme-Linked Immunosorbent,Enzyme Linked Immunosorbent Assay,Enzyme-Linked Immunosorbent Assays,Immunosorbent Assay, Enzyme-Linked,Immunosorbent Assays, Enzyme-Linked
D004970 Estrone An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. Folliculin (Hormone),Estrone, (+-)-Isomer,Estrone, (8 alpha)-Isomer,Estrone, (9 beta)-Isomer,Estrovarin,Kestrone,Unigen,Wehgen
D005260 Female Females
D005498 Follicular Phase The period of the MENSTRUAL CYCLE representing follicular growth, increase in ovarian estrogen (ESTROGENS) production, and epithelial proliferation of the ENDOMETRIUM. Follicular phase begins with the onset of MENSTRUATION and ends with OVULATION. Menstrual Cycle, Follicular Phase,Menstrual Cycle, Proliferative Phase,Menstrual Proliferative Phase,Preovulatory Phase,Phase, Follicular,Phase, Menstrual Proliferative,Phase, Preovulatory,Proliferative Phase, Menstrual

Related Publications

M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Measurement of estrone-3-glucuronide and pregnanediol-3 alpha-glucuronide in early morning urine samples to monitor ovarian function.
July 1989, Journal of bioluminescence and chemiluminescence,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
The Use of Estrone-3-Glucuronide and Pregnanediol-3-Glucuronide Excretion Rates to Navigate the Continuum of Ovarian Activity.
January 2018, Frontiers in public health,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Measurement of estrone-3-glucuronide in urine by rapid, homogeneous time-resolved fluoroimmunoassay.
April 1989, Clinical chemistry,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Ovulation prediction: changes in the concentrations of urinary estrone-3-glucuronide, estradiol-17 beta-glucuronide and estriol-16 alpha-glucuronide during conceptional cycles.
February 1982, Journal of steroid biochemistry,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Preparation of specific antisera to estrone-3-glucuronide and estriol-3-glucuronide.
February 1984, Journal of steroid biochemistry,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Excretion of total estrogens and estrone-3-glucuronide during treatment with human menopausal gonadotropins.
July 1985, European journal of obstetrics, gynecology, and reproductive biology,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
[Parameters of ovulation in spontaneous ovulatory cycles].
October 1984, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Sex steroids in cervical mucus of spontaneous or induced ovulatory cycles.
January 2000, Steroids,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Comparison of two human infant urine collection methods for measuring estrone-3-glucuronide.
July 2021, American journal of physical anthropology,
M I Khatkhatay, and G M Sankolli, and P K Meherji, and V Chowdhury, and U M Joshi
Identifying ovulatory cycles and the day of ovulation by the mis-use of pregnanediol glucuronide excretion rate thresholds.
October 2018, The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception,
Copied contents to your clipboard!