BIOMAT Database Logo BIOMAT Database Logo

The promise of mesenchymal stem cell therapy for acute respiratory distress syndrome. 2018

Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
From the United States Army Institute of Surgical Research (B.A., A.M., A.I.B., L.C.C.), San Antonio, Texas; Oak Ridge Institute for Science and Education (A.M.), Oak Ridge, TN; and The Geneva Foundation (A.I.B.), Tacoma, Washington.

This review describes the current state of the science on mesenchymal stem cell (MSC) treatment for acute lung injury (ALI). The general characteristics, regenerative potential, and mechanism of action of MSCs are first presented. Next, particular emphasis is placed on the application of MSCs for the treatment of acute respiratory distress syndrome (ARDS) in preclinical and clinical studies. Finally, we discuss current challenges and future directions in the field presented from a clinician-researcher perspective. The objective of this work is to provide the readership with a current review of the literature discussing the hurdles and overall promise of MSCs as therapeutic interventions for the treatment of ARDS.

UI MeSH Term Description Entries
D012128 Respiratory Distress Syndrome A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. ARDS, Human,Acute Respiratory Distress Syndrome,Adult Respiratory Distress Syndrome,Pediatric Respiratory Distress Syndrome,Respiratory Distress Syndrome, Acute,Respiratory Distress Syndrome, Adult,Respiratory Distress Syndrome, Pediatric,Shock Lung,Distress Syndrome, Respiratory,Distress Syndromes, Respiratory,Human ARDS,Lung, Shock,Respiratory Distress Syndromes,Syndrome, Respiratory Distress
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D045164 Mesenchymal Stem Cell Transplantation Transfer of MESENCHYMAL STEM CELLS between individuals within the same species (TRANSPLANTATION, HOMOLOGOUS) or transfer within the same individual (TRANSPLANTATION, AUTOLOGOUS). Stem Cell Transplantation, Mesenchymal,Transplantation, Mesenchymal Stem Cell
D055371 Acute Lung Injury A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). Lung Injury, Acute,Acute Lung Injuries,Lung Injuries, Acute

Related Publications

Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Genetically modified mesenchymal stem cell therapy for acute respiratory distress syndrome.
December 2019, Stem cell research & therapy,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
The Promise of Mesenchymal Stem Cells Therapy for Acute Respiratory Distress Syndrome Caused by COVID-19.
January 2021, Current stem cell research & therapy,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome.
January 2016, F1000Research,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Mesenchymal stem cell therapy for acute respiratory distress syndrome: from basic to clinics.
October 2020, Protein & cell,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Mesenchymal stem cells - a promising therapy for Acute Respiratory Distress Syndrome.
January 2012, F1000 medicine reports,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Mesenchymal stem cells: a promising therapy for the acute respiratory distress syndrome.
January 2013, Respiration; international review of thoracic diseases,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Stem cell therapy in acute respiratory distress syndrome.
March 2009, Revista Brasileira de terapia intensiva,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Mesenchymal Stem/Stromal Cells Therapy for Sepsis and Acute Respiratory Distress Syndrome.
February 2021, Seminars in respiratory and critical care medicine,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Mesenchymal stem cell therapy for acute respiratory distress syndrome: a light at the end of the tunnel?
February 2015, Anesthesiology,
Ben Antebi, and Arezoo Mohammadipoor, and Andriy I Batchinsky, and Leopoldo C Cancio
Cell therapy demonstrates promise for acute respiratory distress syndrome - but which cell is best?
March 2013, Stem cell research & therapy,
Copied contents to your clipboard!