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Serum LDH-isoenzyme studies revealed that in carcinoma cervix, the principal activity was confined to LDH-2 and LDH-3 with a significant rise in LDH-2 fraction when compared with the control values (P less than 0.001). Radiotherapy caused significant lowering of LDH-2 and LDH-3 (P less than 0.001 in each case). There was no relation of LDH-isoenzyme distribution in different clinical stages and morphological distribution within the tumor. Further, LDH-2 and LDH-3 were found to be lowered significantly in good and moderate clinical radiation response (CRR) groups (P less than 0.001 in each case) but in poor CRR group no significant change in LDH-2 and LDH-3 was observed following radiotherapy. LDH-isoenzyme determination in carcinoma cervix is very helpful in assessing the treatment response following radiotherapy and thus may be an important prognostic parameter.
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
January 1970,
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
March 1970,
Clinical biochemistry,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
December 1976,
Leber, Magen, Darm,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
September 1966,
British heart journal,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
January 1979,
Journal of postgraduate medicine,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
December 1962,
Lancet (London, England),
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
May 1968,
The Manchester medical gazette,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
June 1969,
The Indian journal of medical research,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
May 1971,
The American journal of gastroenterology,
M Kumar, and
A Birdi, and
Y N Gupta, and
S Gupta
December 1971,
Journal of the American Geriatrics Society,
