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The aim of this study was to examine whether a vaginal Escherichia coli colonization, mimicking the one seen in UTI-prone females, could be induced by amoxicillin administration. In adult cynomolgus monkeys, who carry the alpha-Gal-1-4-beta-Gal receptor for P-fimbriae, we have investigated the ability of a clinical isolate of P-fimbriated E. coli to colonize the mucous membranes of the genital tract. When the vagina was washed with a suspension of the P-fimbriated strain, a persistent colonization was obtained in only 17% (4/24) of the experiments. When such colonization attempts were performed during vaginal amoxicillin administration, a persistent and heavy colonization of the vagina occurred in 5/5 attempts. The findings do not contradict our hypothesis that antibiotics given to UTI-prone females may facilitate the establishment of the abnormal colonization of the genital tract.
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
August 1977,
La Clinica terapeutica,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
December 2001,
The Indian journal of medical research,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
January 1976,
Turk hijiyen ve tecrubi biyoloji dergisi,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
April 1988,
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
June 1974,
The Journal of infectious diseases,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
August 1977,
The Journal of infectious diseases,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
November 2005,
Infection and immunity,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
May 1972,
Das Deutsche Gesundheitswesen,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
February 1976,
Minerva pediatrica,
B M Herthelius, and
K G Hedström, and
R Möllby, and
C E Nord, and
L Pettersson, and
J Winberg
January 1984,
Medycyna doswiadczalna i mikrobiologia,
