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Naive pluripotent stem cells as a model for studying human developmental epigenomics: opportunities and limitations. 2017

Peter J Rugg-Gunn
Epigenetics Programme, Babraham Institute, Babraham, Cambridge, CB22 3AT, UK.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D049951 X Chromosome Inactivation A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females. X Inactivation,Lyon Hypothesis,Lyonization,X-Inactivation,Chromosome Inactivation, X,Hypothesis, Lyon,Inactivation, X,Inactivation, X Chromosome,X Inactivations
D053595 Embryonic Stem Cells Cells derived from the BLASTOCYST INNER CELL MASS which forms before implantation in the uterine wall. They retain the ability to divide, proliferate and provide progenitor cells that can differentiate into specialized cells. Stem Cells, Embryonic,Cell, Embryonic Stem,Cells, Embryonic Stem,Embryonic Stem Cell,Stem Cell, Embryonic
D057890 Epigenomics The systematic study of the global gene expression changes due to EPIGENETIC PROCESSES and not due to DNA base sequence changes. Epigenetics,Epigenetic,Epigenomic
D019175 DNA Methylation Addition of methyl groups to DNA. DNA methyltransferases (DNA methylases) perform this reaction using S-ADENOSYLMETHIONINE as the methyl group donor. DNA Methylations,Methylation, DNA,Methylations, DNA

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