Biomaterial Database

The ultrastructural localization of the corrosion products of dental amalgam. 1979

G Ellender, and K N Ham, and J K Harcourt

The ultrastructural localization of corrosion products released from dental amalgam implants in rat subcutaneous tissue was studied by means of a sulphide-silver technique. Implants stimulated a prolonged inflammatory response with delayed granulation tissue formation and slow and faulty collagen formation. The metallic corrosion products were found both in cells and in association with matrix components. Intracellular metal deposits were predominantly in the cytoplasmic matrix and in vacuoles in the early (19 day) lesions, but at 60 days there was metal in many nuclei, both viable and dead. Collagen fibrils had metal on the surface and vascular basement membranes had granules of bound metals.

UI	MeSH Term	Description	Entries
D002196	Capillaries	The minute vessels that connect arterioles and venules.	Capillary Beds,Sinusoidal Beds,Sinusoids,Bed, Sinusoidal,Beds, Sinusoidal,Capillary,Capillary Bed,Sinusoid,Sinusoidal Bed
D002627	Chemistry, Physical	The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.	Physical Chemistry,Chemistries, Physical,Physical Chemistries
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D003343	Corrosion	The gradual destruction of a metal or alloy due to oxidation or action of a chemical agent. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)	Corrosions
D003723	Dental Amalgam	An alloy used in restorative dentistry that contains mercury, silver, tin, copper, and possibly zinc.	Amalgam, Dental,Amalgams, Dental,Dental Amalgams
D003757	Dental Implantation	The grafting or inserting of a prosthetic device of alloplastic material into the oral tissue beneath the mucosal or periosteal layer or within the bone. Its purpose is to provide support and retention to a partial or complete denture.	Dental Implant Therapy,Dental Prosthesis Implantation,Implantation, Dental,Implantation, Dental Prosthesis,Prosthesis Implantation, Dental,Dental Implant Therapies,Dental Prosthesis Implantations,Implant Therapy, Dental,Therapy, Dental Implant
D004727	Endothelium	A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.	Endotheliums
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012867	Skin	The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.