The Chemical Club (fl. 1806-1828) was a small scientific dining club in London. Among its members were Sir Humphry Davy, William Hyde Wollaston, and Alexander Marcet. Other accomplished men of science, including John Dalton, Jöns Jacob Berzelius, and Augustin Pyramus de Candolle, also attended its meetings as guests. This article, drawing on the unpublished papers of Lionel Felix Gilbert, as well as a range of contemporary sources in print and manuscript, presents the first substantial history of the Chemical Club, and situates it in the context of the scientific and social networks of the period. It aims to enrich our understanding of the scientific culture of the early nineteenth century in Britain by tracing the Club's influence on, or connection to, some of the most pioneering and transformative scientific work of the first quarter of the 1800s, such as the discovery of nitrogen trichloride, the invention of the miners' safety lamp, and Hans Christian Ørsted's work on electromagnetism.