Piriprost: a selective inhibitor of leukotriene synthesis. 1985

M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards

UI MeSH Term Description Entries
D009504 Neutrophils Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D011464 Epoprostenol A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY). Prostacyclin,Prostaglandin I2,Epoprostanol,Epoprostenol Sodium,Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer,Flolan,Prostaglandin I(2),Veletri
D004195 Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. Animal Disease Model,Animal Disease Models,Disease Model, Animal
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006168 Guinea Pigs A common name used for the genus Cavia. The most common species is Cavia porcellus which is the domesticated guinea pig used for pets and biomedical research. Cavia,Cavia porcellus,Guinea Pig,Pig, Guinea,Pigs, Guinea
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000882 Haplorhini A suborder of PRIMATES consisting of six families: CEBIDAE (some New World monkeys), ATELIDAE (some New World monkeys), CERCOPITHECIDAE (Old World monkeys), HYLOBATIDAE (gibbons and siamangs), CALLITRICHINAE (marmosets and tamarins), and HOMINIDAE (humans and great apes). Anthropoidea,Monkeys,Anthropoids,Monkey
D001249 Asthma A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL). Asthma, Bronchial,Bronchial Asthma,Asthmas
D013189 SRS-A A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a "slow-reacting substance of ANAPHYLAXIS" released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed) Slow Reacting Substance of Anaphylaxis

Related Publications

M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
September 1987, Pediatric research,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
January 1993, Journal of lipid mediators,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
June 2006, Phytomedicine : international journal of phytotherapy and phytopharmacology,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
October 1986, Thorax,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
January 1984, Biochimica et biophysica acta,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
February 1986, Biochemical pharmacology,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
January 1983, Advances in prostaglandin, thromboxane, and leukotriene research,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
September 1984, The Journal of allergy and clinical immunology,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
February 2021, Journal of medicinal chemistry,
M K Bach, and B J Bowman, and J R Brashler, and F A Fitzpatrick, and R L Griffin, and H G Johnson, and N J Major, and J C McGuire, and M L McNee, and I M Richards
March 1993, Agents and actions,
Copied contents to your clipboard!