Biomaterial Database

[Beta-endorphin levels in the blood and cerebrospinal fluid in humans]. 1985

B Radzikowska, and A Szczudlik, and A Lypka

Beta-endorphin concentrations were determined in the cerebrospinal fluid and blood before and after lumbar tap in 19 patients with lumbosacral pains. No statistically significant difference was observed in this concentration before and after lumbar tap, although in individual cases a significant rise of beta-endorphin occurred. The mean beta-endorphin concentration in blood was about twice as high as in the cerebrospinal fluid. No correlation was noticed between the concentration of beta-endorphin in blood and in CSF.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D004723	Endorphins	One of the three major groups of endogenous opioid peptides. They are large peptides derived from the PRO-OPIOMELANOCORTIN precursor. The known members of this group are alpha-, beta-, and gamma-endorphin. The term endorphin is also sometimes used to refer to all opioid peptides, but the narrower sense is used here; OPIOID PEPTIDES is used for the broader group.	Endorphin
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001416	Back Pain	Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.	Backache,Back Ache,Back Pain with Radiation,Back Pain without Radiation,Vertebrogenic Pain Syndrome,Ache, Back,Aches, Back,Back Aches,Back Pains,Backaches,Pain Syndrome, Vertebrogenic,Pain Syndromes, Vertebrogenic,Pain, Back,Pains, Back,Syndrome, Vertebrogenic Pain,Syndromes, Vertebrogenic Pain,Vertebrogenic Pain Syndromes
D001615	beta-Endorphin	A 31-amino acid peptide that is the C-terminal fragment of BETA-LIPOTROPIN. It acts on OPIOID RECEPTORS and is an analgesic. Its first four amino acids at the N-terminal are identical to the tetrapeptide sequence of METHIONINE ENKEPHALIN and LEUCINE ENKEPHALIN.	Endorphin, beta,beta-Endorphin (1-31),beta Endorphin
D012585	Sciatica	A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.	Neuralgia, Sciatic,Sciatic Neuralgia,Sciatica, Bilateral,Bilateral Sciatica,Bilateral Sciaticas,Neuralgias, Sciatic,Sciatic Neuralgias