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Ketanserin is a pure antagonist of serotonin S2-receptors, in blood vessels, platelets and bronchial tissue. Ketanserin has been suggested as hypotensive drug in man, but it shows as well a specific activity on platelet aggregation. An increased incidence of hypertension, of unknown origin, has been found in patients with chronic alcoholism: hypotheses have been made upon an increased incretion of catecholamines and a greater sensitivity of blood vessels' receptors to their action. The data from the present study of eleven patients show that these subjects had an increased platelet activity and ketanserin administration was effective in allowing both the blood pressure levels and platelet activity to resume their normal range. This drug is thus suggested, for its pharmacological properties, as an elective medication for hypertensive patients with chronic alcoholism.
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
November 1984,
British journal of clinical pharmacology,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
January 1988,
Journal of cardiovascular pharmacology,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
November 1987,
Chest,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
March 1987,
International journal of cardiology,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
June 1990,
Ugeskrift for laeger,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
January 1984,
Lancet (London, England),
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
January 1984,
Clinical and experimental hypertension. Part A, Theory and practice,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
June 1983,
Archives internationales de pharmacodynamie et de therapie,
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
May 1992,
Archives of ophthalmology (Chicago, Ill. : 1960),
A De Lorenzo, and
M Ceccanti, and
M Romeo, and
M Pisculli, and
M G Di Giovanni, and
A Lais, and
G Assogna, and
F C Valgiusti
January 1985,
Journal of cardiovascular pharmacology,
