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Silicone implants were placed in the nasal, cheek, and chin areas in children with Down's syndrome to improve facial appearance. Clinical and radiologic follow-up evaluation revealed significant crater-like bone resorption in the mandibular symphysis in 75% of the cases. All of these implants were removed, and the bone showed regrowth to the presurgical state. No sign of bone damage was present in the malar or nasal areas.
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