Biomaterial Database

Effect of pulse rate variation on blood flow through axisymmetric and asymmetric stenotic artery models. 2018

Tapan Sood, and Somnath Roy, and Manabendra Pathak

Department of Mechanical Engineering, Indian Institute of Technology Patna, Bihta, Bihar 801103, India. Electronic address: SOOD_TAPAN@ongc.co.in.

The present work reports numerical simulations of blood flow patterns and wall shear stress (WSS) distributions in stenotic arteries, modelled as straight tubes. Inflow waveforms have been generated for different pulse rates considering constant volumetric flow during each pulsation cycle and a two-element windkessel model has been used to specify the outlet pressure. It is noticed that the non-Newtonian shear thinning rheology of blood produces more accurate and realistic predictions of the flow field as compared to the Newtonian assumption. Further, the effects of variation of pulse rates on the spatial and temporal distribution of WSS and oscillatory shear index (OSI) have also been studied for both axisymmetric and asymmetric stenosis. The changes in the mean flow features due to changes in pulsation frequencies have also been reported.

UI	MeSH Term	Description	Entries
D008962	Models, Theoretical	Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.	Experimental Model,Experimental Models,Mathematical Model,Model, Experimental,Models (Theoretical),Models, Experimental,Models, Theoretic,Theoretical Study,Mathematical Models,Model (Theoretical),Model, Mathematical,Model, Theoretical,Models, Mathematical,Studies, Theoretical,Study, Theoretical,Theoretical Model,Theoretical Models,Theoretical Studies
D011673	Pulsatile Flow	Rhythmic, intermittent propagation of a fluid through a BLOOD VESSEL or piping system, in contrast to constant, smooth propagation, which produces laminar flow.	Flow, Pulsating,Perfusion, Pulsatile,Flow, Pulsatile,Flows, Pulsatile,Flows, Pulsating,Perfusions, Pulsatile,Pulsatile Flows,Pulsatile Perfusion,Pulsatile Perfusions,Pulsating Flow,Pulsating Flows
D003198	Computer Simulation	Computer-based representation of physical systems and phenomena such as chemical processes.	Computational Modeling,Computational Modelling,Computer Models,In silico Modeling,In silico Models,In silico Simulation,Models, Computer,Computerized Models,Computer Model,Computer Simulations,Computerized Model,In silico Model,Model, Computer,Model, Computerized,Model, In silico,Modeling, Computational,Modeling, In silico,Modelling, Computational,Simulation, Computer,Simulation, In silico,Simulations, Computer
D003251	Constriction, Pathologic	The condition of an anatomical structure's being constricted beyond normal dimensions.	Stenosis,Stricture,Constriction, Pathological,Pathologic Constriction,Constrictions, Pathologic,Pathologic Constrictions,Pathological Constriction,Stenoses,Strictures
D006339	Heart Rate	The number of times the HEART VENTRICLES contract per unit of time, usually per minute.	Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001158	Arteries	The vessels carrying blood away from the heart.	Artery
D057446	Hydrodynamics	The motion of fluids, especially noncompressible liquids, under the influence of internal and external forces.	Fluid Dynamics,Dynamic, Fluid,Dynamics, Fluid,Fluid Dynamic,Hydrodynamic
D018056	Hemorheology	The deformation and flow behavior of BLOOD and its elements i.e., PLASMA; ERYTHROCYTES; WHITE BLOOD CELLS; and BLOOD PLATELETS.	Hemorrheology