Corneal ulcers are considered an ophthalmologic emergency because of their potential to permanently impair vision or perforate the eye. The therapeutic management includes medical therapy and in case of failure, surgical care such as amniotic membrane transplantation. We present the case of a 76-year-old male, admitted for sudden visual loss in the left eye, associated with ocular pain, tearing, and photophobia. The patient was diagnosed with superficial ulcerative keratitis with hypopyon and acute exogenous anterior uveitis for which he underwent medical treatment, both general and topic, with a good evolution during a month. After a month, the patient presented with the corneal ulcer perforated. Surgery was performed in the left eye by covering the ocular surface with an amniotic membrane using the Motowa's sandwich technique. After one year, the same patient was successfully operated for cataract removal and posterior chamber intraocular lens implantation in the left eye.