Controversies in Endoscopic Eradication Therapy for Barrett's Esophagus. 2018

Srinadh Komanduri, and V Raman Muthusamy, and Sachin Wani
Division of Gastroenterology and Hepatology, Northwestern University, Chicago, Illinois. Electronic address: koman1973@gmail.com.

Advances in endoscopic eradication therapy for Barrett's Esophagus-associated neoplasia have resulted in a significant paradigm shift in the diagnosis and management of this complex disease. A robust body of literature critically evaluating outcomes of resection and ablative strategies has allowed gastroenterologists to make quality, evidence-based decisions for their patients. Despite this progress, there are still many unanswered questions and challenges that remain. Ultimately, identification of a cost-effective screening modality, biomarkers for risk stratification, and strides to eliminate post surveillance endoscopy after endoscopic eradication therapy are essential to reach our long-term goal for eradication of esophageal adenocarcinoma.

UI MeSH Term Description Entries
D004945 Esophagoscopy Endoscopic examination, therapy or surgery of the esophagus. Esophagoscopic Surgical Procedures,Surgical Procedures, Esophagoscopic,Esophagoscopic Surgery,Surgery, Esophagoscopic,Esophagoscopic Surgeries,Esophagoscopic Surgical Procedure,Esophagoscopies,Procedure, Esophagoscopic Surgical,Procedures, Esophagoscopic Surgical,Surgeries, Esophagoscopic,Surgical Procedure, Esophagoscopic
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000069916 Endoscopic Mucosal Resection A method for removing lesions from gastrointestinal MUCOUS MEMBRANES. The mucosal tissue with the lesion is elevated by injecting a solution into the submucosal layer underneath it. The elevated tissue with the lesion is then cut out. Endoscopic Full Thickness Resection,Submucosal Tunneling Endoscopic Resection,Endoscopic Mucous Membrane Resection,Endoscopic Submucosal Dissection,Strip Biopsy,Biopsy, Strip,Dissection, Endoscopic Submucosal,Endoscopic Mucosal Resections,Endoscopic Submucosal Dissections,Mucosal Resection, Endoscopic,Resection, Endoscopic Mucosal,Strip Biopsies,Submucosal Dissection, Endoscopic
D001471 Barrett Esophagus A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus. Barrett Syndrome,Esophagus, Barrett,Barrett Epithelium,Barrett Metaplasia,Barrett's Esophagus,Barrett's Syndrome,Barrett Metaplasias,Barretts Esophagus,Barretts Syndrome,Epithelium, Barrett,Esophagus, Barrett's,Metaplasia, Barrett,Metaplasias, Barrett
D017115 Catheter Ablation Removal of tissue with electrical current delivered via electrodes positioned at the distal end of a catheter. Energy sources are commonly direct current (DC-shock) or alternating current at radiofrequencies (usually 750 kHz). The technique is used most often to ablate the AV junction and/or accessory pathways in order to interrupt AV conduction and produce AV block in the treatment of various tachyarrhythmias. Ablation, Transvenous Electric,Catheter Ablation, Electric,Catheter Ablation, Percutaneous,Catheter Ablation, Radiofrequency,Catheter Ablation, Transvenous,Ablation, Catheter,Ablation, Transvenous Electrical,Catheter Ablation, Electrical,Electric Catheter Ablation,Electrical Catheter Ablation,Percutaneous Catheter Ablation,Radiofrequency Catheter Ablation,Transvenous Catheter Ablation,Ablation, Electric Catheter,Ablation, Electrical Catheter,Ablation, Percutaneous Catheter,Ablation, Radiofrequency Catheter,Ablation, Transvenous Catheter,Electric Ablation, Transvenous,Electrical Ablation, Transvenous,Transvenous Electric Ablation,Transvenous Electrical Ablation
D019984 Quality Indicators, Health Care Norms, criteria, standards, and other direct qualitative and quantitative measures used in determining the quality of health care. Global Trigger Tool, Healthcare,Health Metrics,Healthcare Global Trigger Tool,Quality Indicators, Healthcare,Health Metric,Healthcare Quality Indicator,Healthcare Quality Indicators,Indicator, Healthcare Quality,Indicators, Healthcare Quality,Metrics, Health,Quality Indicator, Healthcare

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