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The effect of acute exercise on plasma immunoreactive-atrial natriuretic factor (IR-ANF) was studied in 5 healthy young males subjected to graded exercise on a bicycle ergometer at four different work intensities (approx. 30, 50, 70, and 90% VO2max respectively). Except for the final exercise period, which was continued until exhaustion, all the others were of 30 min duration. Venous blood samples were obtained in the last 2 min of each exercise period. The plasma IR-ANF response to exercise was similar to that of heart rate and systolic blood pressure in that mild exercise in the first stage (corresponding to approx. 30% VO2 max) caused a striking increase of plasma IR-ANF concentrations with a further augmentation in the next stages and a levelling off at exhaustion. Plasma arginine-vasopressin (AVP) and aldosterone (ALDO) rose significantly only in the last two stages, and the highest concentrations were observed at exhaustion. In conclusion, acute exercise stimulates ANF secretion in proportion to the intensity of exercise, while concomitant increases in plasma AVP and ALDO occur only when the work load exceeds the blood lactate (BLA) threshold.
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
June 1985,
Biochemical and biophysical research communications,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
May 1985,
Biochemical and biophysical research communications,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
November 1986,
Clinical and investigative medicine. Medecine clinique et experimentale,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
January 1988,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
September 1986,
Clinical science (London, England : 1979),
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
November 1986,
American heart journal,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
August 1988,
European journal of clinical investigation,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
December 1989,
Journal of applied physiology (Bethesda, Md. : 1985),
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
April 1986,
Biochemical and biophysical research communications,
H Tanaka, and
M Shindo, and
J Gutkowska, and
A Kinoshita, and
H Urata, and
M Ikeda, and
K Arakawa
January 1987,
Contributions to nephrology,
