-transparent.png){kind=logo}
Isolation and sequencing of IR-ANF from plasma reveal that the circulating form of ANF is a 28-amino acid peptide (Ser 99-Tyr 126) which inhibits basal aldosterone secretion from suspensions of rat zona glomerulosa cells to the same extent as synthetic Arg 101-Tyr 126. The same form (minus two N-terminal amino acids) (Arg 101-Tyr 126) has been isolated from culture media of atrial cardiocytes and sequenced. Structure activity studies of shorter, N- or C-terminally truncated versions of synthetic Arg 101-Tyr 126 show that the latter is the most potent one.
Related Publications
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
October 1986,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
November 1988,
Clinical chemistry,
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
August 1987,
Hypertension (Dallas, Tex. : 1979),
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
January 1985,
Nature,
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
January 1985,
Lancet (London, England),
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
October 1991,
Casopis lekaru ceskych,
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
January 1989,
Clinical and experimental hypertension. Part A, Theory and practice,
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
September 1992,
Acta paediatrica (Oslo, Norway : 1992),
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
October 1986,
British heart journal,
M Cantin, and
J Genest, and
G Thibault, and
J Gutkowska, and
R Garcia, and
A De Léan, and
E L Schiffrin, and
C Lazure, and
N G Seidah, and
M Chrétien
January 1996,
Molekuliarna meditsina = Molecular medicine,
