[A case of necrotic metaplasia of the salivary glands (author's transl)]. 1979

C Brocheriou, and J C Bertrand

The authors report a case of necrotic metaplasia of the salivary glands and review the principal clinical, histological, and evolutional characteristics of this rare affection of unknown etiology. The lesion occurs in adults, is located exclusively in the palate and appears as a small usually greatly ulcerated swelling which is sometimes preceded by pain. Histological examination, which requires a relatively deep and fairly large sample, demonstrates a group of modifications essential for diagnosis: ulceration on a inflammatory base with hyperplasic epithelial borders, plus deeper accessory salivary lobules with necrotic plaques and a great deal of malpighian metaplasia, and conservation of normal gland structure. This affection, which is sometimes wrongly diagnosted as a tumor, heals spontaneously within several weeks, which contra-indicates any strong therapeutic measures.

UI MeSH Term Description Entries
D008297 Male Males
D008679 Metaplasia A condition in which there is a change of one adult cell type to another similar adult cell type.
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009336 Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D010157 Palatal Neoplasms Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA. Neoplasm, Palatal,Neoplasms, Palatal,Palatal Neoplasm
D010159 Palate The structure that forms the roof of the mouth. It consists of the anterior hard palate (PALATE, HARD) and the posterior soft palate (PALATE, SOFT). Incisive Papilla,Incisive Papillas,Palates,Papilla, Incisive,Papillas, Incisive
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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