-transparent.png){kind=logo}
The effects of intracerebroventricular injection of atrial natriuretic polypeptide (ANP) and angiotensin II (AII) on the concentration of dopamine, noradrenaline, serotonin and their primary metabolites in the rat brain were studied using high performance liquid chromatography with electrochemical detection. ANP (2 and 5 micrograms) decreased the level of dopamine and its metabolite in the septum and hypothalamus. In contrast, AII (100 ng) increased their levels in these brain regions. The simultaneous administration of ANP (5 micrograms) with AII (100 ng) resulted in a marked reduction of the AII-induced increase of dopamine and its metabolite. No significant changes were observed in the concentrations of noradrenaline and serotonin throughout the brain. These results suggest that the central action of ANP is mediated in part via the dopaminergic system.
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
November 1991,
Brain research bulletin,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
August 1990,
Neuroscience letters,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
January 1989,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
September 1989,
Cellular and molecular neurobiology,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
September 2001,
Neurosurgery,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
August 1987,
Acta endocrinologica,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
June 1987,
The American journal of physiology,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
May 1986,
Clinical and experimental pharmacology & physiology,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
August 1992,
Neuroendocrinology,
K Nakao, and
G Katsuura, and
N Morii, and
H Itoh, and
S Shiono, and
T Yamada, and
A Sugawara, and
M Sakamoto, and
Y Saito, and
M Eigyo
January 1996,
Brain research bulletin,
