Evaluation of the measurement of blood glucose levels on dried filter paper blood spots. 1985

P H Winocour, and G A McKinnon, and J R McMurray, and D C Anderson

The measurement of blood glucose using discs punched from dried spots on filter paper has been examined as a method to monitor patients' home blood glucose results. We confirm that the method is precise, reproducible, and accurate, but show that impregnation of the filter paper with boric acid leads to an initial false elevation in measured glucose levels and does not improve stability of the sample more than does refrigeration. Degradation of blood glucose is insignificant over 28 days if samples are stored at -20 degrees C, and samples kept at 4 degrees C show minimal falls provided they are analysed within 7 days. The greatest breakdown of glucose was shown to occur during the first 48 hours after application. The filter paper glucose measurements correlated closely with parallel measurements using a Yellow Springs Glucose Analyser.

UI MeSH Term Description Entries
D008991 Monitoring, Physiologic The continuous measurement of physiological processes, blood pressure, heart rate, renal output, reflexes, respiration, etc., in a patient or experimental animal; includes pharmacologic monitoring, the measurement of administered drugs or their metabolites in the blood, tissues, or urine. Patient Monitoring,Monitoring, Physiological,Physiologic Monitoring,Monitoring, Patient,Physiological Monitoring
D010209 Paper Thin sheets made from wood pulp and other fibrous substances, used for writing, drawing, printing, image duplication or wrapping. Papers
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D003920 Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012648 Self Care Caring for self when ill or positive actions and adopting behaviors to prevent illness. Self-Care,Care, Self

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