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Twelve patients with primary amyloidosis (AL) were investigated with magnetic resonance imaging (MRI). In 9 patients an abnormal thickening of the heart walls was present and in 2 macroglossia was found at MRI. T1 was significantly increased in liver (p less than 0.05) and subcutaneous fat (p less than 0.01) while it was decreased in the spleen (p less than 0.05). T2 was significantly decreased (p less than 0.01) in the spleen in patients with amyloidosis, while it was not significantly altered in the liver or subcutaneous fat. After therapy T1 of the liver was reduced towards normal values in 4 patients. It is concluded that MRI might be a method to quantitate the amount of amyloid deposits in the tissue, and that the effect of therapy may be monitored with this technique.
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
April 2000,
Internal medicine (Tokyo, Japan),
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
August 2004,
Urology,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
December 2009,
JACC. Cardiovascular imaging,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
September 2005,
Revista espanola de cardiologia,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
January 2016,
QJM : monthly journal of the Association of Physicians,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
August 2019,
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
December 2009,
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
January 1989,
Acta cardiologica,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
January 2009,
Radiologia,
L Benson, and
A Hemmingsson, and
A Ericsson, and
B Jung, and
G Sperber, and
K A Thuomas, and
P Westermark
March 2007,
Acta radiologica (Stockholm, Sweden : 1987),
