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50 year old men with moderate, essential hypertension (n = 39) were compared to normotensive males of similar age (n = 31). The hypertensive men were heavier (10 kg in average, p less than 0.01), and had a higher pulse rate (5 beats per minute (p less than 0.05). Plasma beta-thromboglobulin, a marker of platelet release reaction, was 49% higher in the hypertensive group (p less than 0.01). Total cholesterol, LDL + VLDL cholesterol and serum triglycerides were not significantly different between the groups. In the hypertensive group, plasma beta-thromboglobulin concentration correlated significantly with total cholesterol (r = 0.47, p less than 0.01) as well as with LDL + VLDL cholesterol (r = 0.50, p less than 0.01). In the normotensive group no such correlation was found. The results suggest activation of platelets in hypertension, and suggest that in hypertension, even a normal cholesterol concentration may influence platelet function.
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
June 1983,
Scandinavian journal of clinical and laboratory investigation,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
January 1990,
Journal of psychosomatic research,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
January 1979,
Upsala journal of medical sciences,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
January 1978,
Scandinavian journal of rheumatology,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
January 1976,
Upsala journal of medical sciences,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
May 1996,
Blood pressure,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
February 1972,
American journal of epidemiology,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
July 1997,
Blood pressure,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
December 2002,
Atherosclerosis,
K Gjesdal, and
S E Kjeldsen, and
K Lande, and
A Westheim, and
I Aakesson, and
O P Foss, and
P Leren, and
I K Eide
March 1991,
Atherosclerosis,
