Minimally Invasive management of delayed recognition iatrogenic ureteric injury. 2017

Jessica Morrow, and David Curry, and Maeve Dooher, and Siobhan Woolsey
Department of Urology, Belfast City Hospital, Department of Urology, Craigavon Area Hospital, Co. Down BT63 5QQ.

BACKGROUND Iatrogenic ureteric injuries are a rare but serious complication of abdomino-pelvic surgery which can be associated with significant morbidity. 65-80% of ureteric trauma is only identified in the postoperative period. Current guidelines recommend stent insertion or urinary diversion via percutaneous nephrostomy. Good quality evidence on success and outcomes remains scant and the optimum treatment pathway unknown. METHODS A retrospective review of all delayed presentation ureteric injuries treated in our unit between 2005 and 2013 was performed. Clinical, treatment and outcome data were collected in a custom proforma. RESULTS 19 patients with 21 injured ureters met inclusion criteria. 16/19 (84.2%) injuries were sustained during gynaecological procedures with 10 (52.6%) of these during total abdominal hysterectomy. Suspected mechanisms from diagnostic studies was defined as partial transection in 9/21 (42.9%), complete transection in 3/21 (14.3%) and perforation in 1/21 (4.8%).Median time from injury to presentation was 16 days (IQR 7-25). 11/21 (52.4%) had successful stenting with a median time to stent placement of 25 days (IQR 18.5-42). Those with failed stenting had a median time to attempted stenting of 65 days (IQR 10-91.3). Those with successful stenting 3/11 (27.3%) had resolution requiring no further intervention. 6/11 (54.5%) required open reconstruction, with the remaining two patients unfit for reconstruction and managed with long term stents. With successful stenting median time to definitive surgery was 413 days (IQR 156-476). CONCLUSIONS Success rates for stenting are similar to those reported in the literature (55% vs. 44-59%), but resolution rates are significantly lower (15% vs. 44-80%). Data for an endourological approach as a possible long-term solution is limited by heterogeneity, and a further well conducted multicentre prospective study is required.

UI MeSH Term Description Entries
D007049 Iatrogenic Disease Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment. Hospital-Acquired Condition,Condition, Hospital-Acquired,Conditions, Hospital-Acquired,Disease, Iatrogenic,Diseases, Iatrogenic,Hospital Acquired Condition,Hospital-Acquired Conditions,Iatrogenic Diseases
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D014513 Ureter One of a pair of thick-walled tubes that transports urine from the KIDNEY PELVIS to the URINARY BLADDER. Ureters
D015607 Stents Devices that provide support for tubular structures that are being anastomosed or for body cavities during skin grafting. Stent

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