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Changes in the level of plasma lipids (cholesterol, fatty acids and lipoproteins) were followed in young rats exposed once or repeatedly to hypobaric hypoxia. A single exposure to hypoxia increased the level of LDL lipoproteins but did not influence the concentration of cholesterol and fatty acids in 18-day-old rats. Repeated exposure to hypobaric hypoxia caused a statistically significant increase in the concentration of cholesterol, fatty acids, chylomicra, low density beta-lipoproteins (LDL) and very-low-density beta-lipoproteins (VLDL) in 18-day-old rats, while the level of high-density alpha-lipoproteins (HDL) decreased. In animals that had been repeatedly exposed to hypoxia in their youth, a significant decrease of the LDL lipoprotein fraction was observed at the age of 108 days.
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Basic research in cardiology,
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Respiratory physiology & neurobiology,
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May 2003,
Ceskoslovenska fysiologie,
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January 2004,
Prague medical report,
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June 2011,
Sheng li xue bao : [Acta physiologica Sinica],
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January 2020,
International journal of clinical and experimental pathology,
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January 2020,
Clinical and experimental pharmacology & physiology,
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June 2005,
European journal of applied physiology,
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December 2008,
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