Correlation between intracavernous papaverine injection and Doppler analysis in impotent men. 1987

B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
Department of Surgery, James Buchanan Brady Foundation, New York Hospital-Cornell Medical Center, New York.

One hundred impotent men were evaluated with Doppler pulse-wave analysis and intracavernous papaverine. Fifty-four men with normal Doppler study response had abnormal responses to papaverine. A normal Doppler study response failed to predict the inability of papaverine to induce an erection in 54 per cent of cases. Twenty-seven patients had abnormal Doppler study responses, and only 2 of these men had a normal response to papaverine. An abnormal Doppler study response was highly predictive of a vascular abnormality.

UI MeSH Term Description Entries
D007172 Erectile Dysfunction The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction. Impotence,Male Impotence,Male Sexual Impotence,Dysfunction, Erectile,Impotence, Male,Impotence, Male Sexual,Sexual Impotence, Male
D008297 Male Males
D010208 Papaverine An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. Cerespan,Papaverine Hydrochloride,Pavabid,Pavatym,Hydrochloride, Papaverine
D010410 Penile Erection The state of the PENIS when the erectile tissue becomes filled or swollen (tumid) with BLOOD and causes the penis to become rigid and elevated. It is a complex process involving CENTRAL NERVOUS SYSTEM; PERIPHERAL NERVOUS SYSTEMS; HORMONES; SMOOTH MUSCLES; and vascular functions. Tumescence, Penile,Nocturnal Penile Tumescence,Penile Tumescence,Erection, Penile,Penile Tumescence, Nocturnal,Tumescence, Nocturnal Penile
D010413 Penis The external reproductive organ of males. It is composed of a mass of erectile tissue enclosed in three cylindrical fibrous compartments. Two of the three compartments, the corpus cavernosa, are placed side-by-side along the upper part of the organ. The third compartment below, the corpus spongiosum, houses the urethra. Glans Penis,Penis, Glans
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012212 Rheology The study of the deformation and flow of matter, usually liquids or fluids, and of the plastic flow of solids. The concept covers consistency, dilatancy, liquefaction, resistance to flow, shearing, thixotrophy, and VISCOSITY. Flowmetry,Velocimetry,Velocimetries
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor

Related Publications

B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1991, International urology and nephrology,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
July 1988, The Journal of urology,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1995, International urology and nephrology,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1988, Andrologia,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1988, Annales d'urologie,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1988, Acta urologica Belgica,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
January 1986, Acta Europaea fertilitatis,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
October 1982, Lancet (London, England),
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
April 1988, Ugeskrift for laeger,
B C Mellinger, and E D Vaughan, and S L Thompson, and M Goldstein
February 2002, The Journal of urology,
Copied contents to your clipboard!