| D011565 |
Psoriasis |
A common genetically determined, chronic, inflammatory skin disease characterized by rounded erythematous, dry, scaling patches. The lesions have a predilection for nails, scalp, genitalia, extensor surfaces, and the lumbosacral region. Accelerated epidermopoiesis is considered to be the fundamental pathologic feature in psoriasis. |
Palmoplantaris Pustulosis,Pustular Psoriasis of Palms and Soles,Pustulosis Palmaris et Plantaris,Pustulosis of Palms and Soles,Psoriases |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D006893 |
Hydroxyeicosatetraenoic Acids |
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes. |
HETE,Acids, Hydroxyeicosatetraenoic |
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| D000328 |
Adult |
A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. |
Adults |
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| D001092 |
Arachidonate 12-Lipoxygenase |
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS. |
12-Lipoxygenase,Arachidonic Acid 12-Lipoxygenase,12 Lipoxygenase,12-Lipoxygenase, Arachidonate,12-Lipoxygenase, Arachidonic Acid,Arachidonate 12 Lipoxygenase,Arachidonic Acid 12 Lipoxygenase |
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| D012867 |
Skin |
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS. |
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| D019377 |
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid |
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51) |
12-HETE,12-R-HETE,12-S-HETE,12-S-Hydroxyeicosatetraenoic Acid,12 S Hydroxyeicosatetraenoic Acid,Acid, 12-S-Hydroxyeicosatetraenoic |
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| D066298 |
In Vitro Techniques |
Methods to study reactions or processes taking place in an artificial environment outside the living organism. |
In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In |
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