The introduction of modern synthetic suture materials and an individualized approach to wound closure techniques in gynaecological surgery has created new options. Although many issues remain open to question, we have no doubt that catgut and chromic catgut can be declared obsolete in gynaecological surgery. The choice of synthetic suture materials has to be made on personal preferences and clinical experience. If the use of non-absorbable sutures is desired, with few exceptions monofilament suture material is clearly the first choice. Abdominal opening and closure techniques and the selection of appropriate suture materials have to be considered as important factors in minimizing wound healing complications. The decision-making process is based on the knowledge of anatomy, wound healing and possible risk factors. From theoretical considerations, mass closure of all layers apart from skin is considered to be the superior concept. The incidence of incisional hernias and sinus formation will depend on proper technique and possibly the choice of suture material. Some suggestions to individualize opening and closure of the abdomen are made although prospective randomized trials in gynaecology have not yet been performed.