-transparent.png){kind=logo}
Comparative studies of biological properties of influenza A (H3N2) viruses isolated in the epidemics of 1980 and 1983 and in the interepidemic period of 1982 showed a sharp reduction of the biological activity of the interepidemic viruses as compared with that of the epidemic ones. This was manifested by low isolation rate of virus in the interepidemic period, reduced hemagglutinating, interfering, and immunogenic activity of these viruses, poor reproduction in the lung tissue of white mice and the lack of virus-specific syntheses in splenocytes of infected Syrian hamsters. Unlike epidemic strains, the interepidemic strains had ts mutation in gene 6 coding for neuraminidase. There are reasons to associate the observed defect in gene 6 with frequent development of asymptomatic forms of influenza infection in the interepidemic period.
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1989,
Voprosy virusologii,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
September 2019,
Epidemiology and infection,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 2006,
Voprosy virusologii,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
December 2017,
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1980,
Acta microbiologica Bulgarica,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1988,
Bulletin of the World Health Organization,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1987,
Voprosy virusologii,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1960,
Voprosy virusologii,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
January 1985,
Archives of virology,
N A Ivanova, and
L Iu Taros, and
G N Nevedomskaia, and
V K Kudriavtseva, and
T E Medvedeva
June 2015,
Meta gene,
