BIOMAT Database Logo BIOMAT Database Logo

Two genetically diverse H7N7 avian influenza viruses isolated from migratory birds in central China. 2018

Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, 430071, China.

After the emergence of H7N9 avian influenza viruses (AIV) in early 2013 in China, active surveillance of AIVs in migratory birds was undertaken, and two H7N7 strains were subsequently recovered from the fresh droppings of migratory birds; the strains were from different hosts and sampling sites. Phylogenetic and sequence similarity network analyses indicated that several genes of the two H7N7 viruses were closely related to those in AIVs circulating in domestic poultry, although different gene segments were implicated in the two isolates. This strongly suggested that genes from viruses infecting migratory birds have been introduced into poultry-infecting strains. A Bayesian phylogenetic reconstruction of all eight segments implied that multiple reassortments have occurred in the evolution of these viruses, particularly during late 2011 and early 2014. Antigenic analysis using a hemagglutination inhibition test showed that the two H7N7 viruses were moderately cross-reactive with H7N9-specific anti-serum. The ability of the two H7N7 viruses to remain infectious under various pH and temperature conditions was evaluated, and the viruses persisted the longest at near-neutral pH and in cold temperatures. Animal infection experiments showed that the viruses were avirulent to mice and could not be recovered from any organs. Our results indicate that low pathogenic, divergent H7N7 viruses circulate within the East Asian-Australasian flyway. Virus dispersal between migratory birds and domestic poultry may increase the risk of the emergence of novel unprecedented strains.

UI MeSH Term Description Entries
D007251 Influenza, Human An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia. Grippe,Human Flu,Human Influenza,Influenza in Humans,Influenza,Flu, Human,Human Influenzas,Influenza in Human,Influenzas,Influenzas, Human
D009976 Orthomyxoviridae Infections Virus diseases caused by the ORTHOMYXOVIRIDAE. Orthomyxovirus Infections,Infections, Orthomyxoviridae,Infections, Orthomyxovirus,Swine Influenza,Infection, Orthomyxoviridae,Infection, Orthomyxovirus,Influenza, Swine,Orthomyxoviridae Infection,Orthomyxovirus Infection
D010802 Phylogeny The relationships of groups of organisms as reflected by their genetic makeup. Community Phylogenetics,Molecular Phylogenetics,Phylogenetic Analyses,Phylogenetic Analysis,Phylogenetic Clustering,Phylogenetic Comparative Analysis,Phylogenetic Comparative Methods,Phylogenetic Distance,Phylogenetic Generalized Least Squares,Phylogenetic Groups,Phylogenetic Incongruence,Phylogenetic Inference,Phylogenetic Networks,Phylogenetic Reconstruction,Phylogenetic Relatedness,Phylogenetic Relationships,Phylogenetic Signal,Phylogenetic Structure,Phylogenetic Tree,Phylogenetic Trees,Phylogenomics,Analyse, Phylogenetic,Analysis, Phylogenetic,Analysis, Phylogenetic Comparative,Clustering, Phylogenetic,Community Phylogenetic,Comparative Analysis, Phylogenetic,Comparative Method, Phylogenetic,Distance, Phylogenetic,Group, Phylogenetic,Incongruence, Phylogenetic,Inference, Phylogenetic,Method, Phylogenetic Comparative,Molecular Phylogenetic,Network, Phylogenetic,Phylogenetic Analyse,Phylogenetic Clusterings,Phylogenetic Comparative Analyses,Phylogenetic Comparative Method,Phylogenetic Distances,Phylogenetic Group,Phylogenetic Incongruences,Phylogenetic Inferences,Phylogenetic Network,Phylogenetic Reconstructions,Phylogenetic Relatednesses,Phylogenetic Relationship,Phylogenetic Signals,Phylogenetic Structures,Phylogenetic, Community,Phylogenetic, Molecular,Phylogenies,Phylogenomic,Reconstruction, Phylogenetic,Relatedness, Phylogenetic,Relationship, Phylogenetic,Signal, Phylogenetic,Structure, Phylogenetic,Tree, Phylogenetic
D011200 Poultry Domesticated birds raised for food. It typically includes CHICKENS; TURKEYS, DUCKS; GEESE; and others. Fowls, Domestic,Domestic Fowl,Domestic Fowls,Fowl, Domestic,Poultries
D002681 China A country spanning from central Asia to the Pacific Ocean. Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D005585 Influenza in Birds Infection of domestic and wild fowl and other BIRDS with INFLUENZA A VIRUS. Avian influenza usually does not sicken birds, but can be highly pathogenic and fatal in domestic POULTRY. Avian Flu,Avian Influenza,Fowl Plague,Influenza, Avian,Avian Influenzas,Flu, Avian,Influenza in Bird,Influenzas, Avian,Plague, Fowl
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000835 Animals, Wild Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available. Animals, Nondomestic,Animals, Nondomesticated,Animals, Feral,Stray Animals,Animal, Feral,Animal, Nondomestic,Animal, Nondomesticated,Animal, Stray,Animal, Wild,Animals, Stray,Feral Animal,Feral Animals,Nondomestic Animal,Nondomestic Animals,Nondomesticated Animal,Nondomesticated Animals,Stray Animal,Wild Animal,Wild Animals
D001499 Bayes Theorem A theorem in probability theory named for Thomas Bayes (1702-1761). In epidemiology, it is used to obtain the probability of disease in a group of people with some characteristic on the basis of the overall rate of that disease and of the likelihood of that characteristic in healthy and diseased individuals. The most familiar application is in clinical decision analysis where it is used for estimating the probability of a particular diagnosis given the appearance of some symptoms or test result. Bayesian Analysis,Bayesian Estimation,Bayesian Forecast,Bayesian Method,Bayesian Prediction,Analysis, Bayesian,Bayesian Approach,Approach, Bayesian,Approachs, Bayesian,Bayesian Approachs,Estimation, Bayesian,Forecast, Bayesian,Method, Bayesian,Prediction, Bayesian,Theorem, Bayes

Related Publications

Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020.
January 2022, Microbes and infection,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Novel Avian Influenza A(H5N8) Viruses in Migratory Birds, China, 2013-2014.
June 2016, Emerging infectious diseases,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Isolation of two novel reassortant H3N6 avian influenza viruses from long-distance migratory birds in Jiangxi Province, China.
August 2020, MicrobiologyOpen,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Pathogenic assessment of avian influenza viruses in migratory birds.
December 2021, Emerging microbes & infections,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Migratory birds reinforce local circulation of avian influenza viruses.
January 2014, PloS one,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Prevalence, evolution, replication and transmission of H3N8 avian influenza viruses isolated from migratory birds in eastern China from 2017 to 2021.
December 2023, Emerging microbes & infections,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Isolation and identification of avian influenza viruses from migratory birds in Iran.
October 2005, The Veterinary record,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Genetic characterization of H1 avian influenza viruses isolated from migratory birds and domestic ducks in Korea.
February 2011, Virus genes,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Genetics, pathogenicity and transmissibility of novel reassortant H5N6 highly pathogenic avian influenza viruses first isolated from migratory birds in western China.
January 2018, Emerging microbes & infections,
Haizhou Liu, and Chaochao Xiong, and Jing Chen, and Guang Chen, and Jun Zhang, and Yong Li, and Yanping Xiong, and Runkun Wang, and Ying Cao, and Quanjiao Chen, and Di Liu, and Hanzhong Wang, and Jianjun Chen
Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020.
December 2021, Emerging microbes & infections,
Copied contents to your clipboard!