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Fractionated whole body X-irradiation (4 X 1.75 Gy at weekly intervals) induces a high percentage of thymic lymphomas in C57BL/Ka mice. These tumors develop after a long latency period during which the thymic lymphopoiesis is deeply altered. In the present work, we test wether those modifications are due to lack of prothymocyte homing to preleukemic thymuses. Our results show that the preleukemic state of the thymus don't prevent the homing of normal marrow precursors grafted immediately after an irradiation of 4 Gy. Thus the alterations of thymic lymphopoiesis observed after a leukemogenic irradiation are not due to a modification in the thymus receptivity to thymocyte precursors.
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
February 1981,
Cancer research,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
January 1982,
Comptes rendus des seances de la Societe de biologie et de ses filiales,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
January 1985,
International journal of radiation oncology, biology, physics,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
November 1986,
Journal of the National Cancer Institute,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
November 1971,
Strahlentherapie,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
October 1973,
Cancer,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
January 1988,
Thymus,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
October 1989,
International journal of radiation oncology, biology, physics,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
January 1982,
Radiobiologiia,
C Humblet, and
M P Defresne, and
R Greimers, and
A M Rongy, and
J Boniver
December 1986,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
