Prevention of horizontal transmission of hepatitis B: efficacy of hepatitis B immunoglobulin and vaccine in an institution for the handicapped. 1988

K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

In a Japanese institution for the handicapped with confirmed continuous outbreaks of hepatitis B virus (HBV) infection by horizontal nosocomial transmission, 29 susceptible subjects (8 institutionalized children and 21 medical staff) were injected intramuscularly with anti-human HBs immunoglobulin (HB Ig) and subcutaneously with HB vaccine. All cases acquired HBs antibody after injection of HB Ig and seropositivity for HB after the third inoculation of HB vaccine was 78.6%. No new case of HB occurred among the study population throughout the period investigated. This suggested the effectiveness of HB Ig and HB vaccine in the prevention of horizontal nosocomial transmission of HBV.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007136 Immunoglobulins Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. Globulins, Immune,Immune Globulin,Immune Globulins,Immunoglobulin,Globulin, Immune
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003428 Cross Infection Any infection which a patient contracts in a health-care institution. Hospital Infections,Nosocomial Infections,Health Care Associated Infection,Health Care Associated Infections,Healthcare Associated Infections,Infection, Cross,Infections, Hospital,Infections, Nosocomial,Cross Infections,Healthcare Associated Infection,Hospital Infection,Infection, Healthcare Associated,Infection, Hospital,Infection, Nosocomial,Infections, Cross,Infections, Healthcare Associated,Nosocomial Infection
D006233 Disabled Persons Persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations. Handicapped,People with Disabilities,Persons with Disabilities,Physically Challenged,Physically Handicapped,Physically Disabled,Disabilities, People with,Disabilities, Persons with,Disability, Persons with,Disabled Person,Disabled, Physically,Handicapped, Physically,People with Disability,Person, Disabled,Persons with Disability,Persons, Disabled
D006509 Hepatitis B INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact. Hepatitis B Virus Infection
D006510 Hepatitis B Antibodies Antibodies to the HEPATITIS B ANTIGENS, including antibodies to the surface (Australia) and core of the Dane particle and those to the "e" antigens. Anti-Australia Antigens,Anti-HBAg,Anti-Hepatitis B Antigens,Anti HBAg,Hepatitis B Virus Antibodies,Anti Australia Antigens,Anti Hepatitis B Antigens,Antibodies, Hepatitis B,Antigens, Anti-Australia,Antigens, Anti-Hepatitis B,B Antibodies, Hepatitis,B Antigens, Anti-Hepatitis,HBAg, Anti
D006514 Hepatitis B Surface Antigens Those hepatitis B antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen. Australia Antigen,HBsAg,Hepatitis B Surface Antigen,Antigen, Australia
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
July 1989, Minerva pediatrica,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
May 2015, Genetics and molecular research : GMR,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
February 1983, Gastroenterologia Japonica,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
January 1993, Infection,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
December 1992, The New England journal of medicine,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
January 1988, La Pediatria medica e chirurgica : Medical and surgical pediatrics,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
January 1983, Pediatric infectious disease,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
May 1987, JAMA,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
August 1988, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada,
K Ueda, and K Tokugawa, and Y Hashiguchi, and S Matsumoto, and H Uchimura, and T Shigaki, and Y Ishihara, and K Mizuno, and A Tashiro, and S Nonaka
January 1995, Revista espanola de salud publica,
Copied contents to your clipboard!