Biomaterial Database

Secondary Prevention Strategies for Nonmelanoma Skin Cancer. 2018

Adriana T Lopez, and Richard D Carvajal, and Larisa Geskin

Skin cancer is the most commonly diagnosed cancer in the United States and has become a major public health problem that continues to grow. Despite numerous initiatives and increased public awareness of the dangers of skin cancer, the incidence of skin cancer continues to rise worldwide. This highlights the need for a critical review of existing skin cancer prevention strategies as a means to determine where targeted efforts may improve patient outcomes. In this article, we review the published literature and evaluate secondary prevention strategies for nonmelanoma skin cancer. Specifically, we examine the existing data on the use of chemopreventive agents for nonmelanoma skin cancer primarily in immunocompetent individuals, but also in organ transplant recipients, the best-studied immunosuppressed population. We also explore investigational therapies proposed for chemoprevention of nonmelanoma skin cancers.

UI	MeSH Term	Description	Entries
D010778	Photochemotherapy	Therapy using oral or topical photosensitizing agents with subsequent exposure to light.	Blue Light Photodynamic Therapy,Photodynamic Therapy,Red Light PDT,Red Light Photodynamic Therapy,Therapy, Photodynamic,Light PDT, Red,PDT, Red Light,Photochemotherapies,Photodynamic Therapies,Therapies, Photodynamic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012878	Skin Neoplasms	Tumors or cancer of the SKIN.	Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D016377	Organ Transplantation	Transference of an organ between individuals of the same species or between individuals of different species.	Grafting, Organ,Transplantation, Organ,Graftings, Organ,Organ Grafting,Organ Graftings,Organ Transplantations,Transplantations, Organ
D055088	Early Detection of Cancer	Methods to identify and characterize cancer in the early stages of disease and predict tumor behavior.	Cancer Screening,Cancer Screening Tests,Early Diagnosis of Cancer,Cancer Early Detection,Cancer Early Diagnosis,Cancer Screening Test,Screening Test, Cancer,Screening Tests, Cancer,Screening, Cancer,Test, Cancer Screening,Tests, Cancer Screening
D055502	Secondary Prevention	The prevention of recurrences or exacerbations of a disease or complications of its therapy.	Disease Prevention, Secondary,Early Therapy,Relapse Prevention,Secondary Disease Prevention,Disease Preventions, Secondary,Early Therapies,Prevention, Relapse,Prevention, Secondary,Prevention, Secondary Disease,Preventions, Relapse,Preventions, Secondary,Preventions, Secondary Disease,Relapse Preventions,Secondary Disease Preventions,Secondary Preventions,Therapies, Early,Therapy, Early
D018890	Chemoprevention	The use of chemical compounds to prevent the development of a specific disease.	Chemoprophylaxis