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Sexual activity was evaluated in 51 women with hirsutism associated with increased levels of circulating androgens before and while on combined treatment with the antiandrogen cyproterone acetate (CA) and ethinyl estradiol (EE2) and compared to a reference group of 52 subjects. The percentage of unbound testosterone (T) was higher (p less than 0.001), the coital frequency lower (p less than 0.05), and the masturbation frequency higher (p less than 0.04) in hirsute women. Mean frequency of total activity (coitus plus masturbation) was similar in the two groups. Treatment with combination of CA and EE2 resulted in a decline of unbound T (p less than 0.001). There was no change of total sexual activity, but coital frequency increased (p less than 0.05) and masturbation frequency declined (p less than 0.04). It is concluded that raised levels of circulating androgens, as judged by free T concentration, are not of crucial importance in the expression of sexual behavior in hirsute women.
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
January 1981,
Panminerva medica,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
March 1976,
The New England journal of medicine,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
January 2015,
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
June 1987,
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
May 1989,
The Journal of clinical endocrinology and metabolism,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
January 1996,
Metabolism: clinical and experimental,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
August 1978,
Fertility and sterility,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
December 1983,
Obstetrics and gynecology,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
January 1991,
Acta endocrinologica,
D A Adamopoulos, and
S Kampyli, and
F Georgiacodis, and
N Kapolla, and
A Abrahamian-Michalakis
January 1984,
Psychotherapy and psychosomatics,
