Biomaterial Database

Binding of trivalent metal ions (Al3+, In3+, La3+) with phosphatidylcholine liposomal membranes investigated by microelectrophoresis. 2018

Joanna Kotyńska, and Zbigniew A Figaszewski

Institute of Chemistry, University of Bialystok, Ciolkowskiego 1K, 15-245, Bialystok, Poland. joannak@uwb.edu.pl.

Interactions between trivalent metal ions (Al3+, In3+, La3+) and phosphatidylcholine (PC) liposomes are studied by microelectrophoresis. The dependence of the PC membrane surface charge density and zeta potential on [Formula: see text] ([Formula: see text] range from 2 to 10) of the aqueous metal chloride solutions is determined. The obtained results indicate the adsorption of Al3+, In3+ and La3+ ions on phosphatidylcholine model membranes, leading to changes in the electrical properties of the membranes. The theoretical considerations on equilibria occurring between phosphatidylcholine liposomal membrane and trivalent metal ions are presented. A mathematical model describing the interactions in a quantitative way is proposed.

UI	MeSH Term	Description	Entries
D007204	Indium	A metallic element, atomic number 49, atomic weight 114.818, symbol In. It is named from its blue line in the spectrum.
D007811	Lanthanum	The prototypical element in the rare earth family of metals. It has the atomic symbol La, atomic number 57, and atomic weight 138.91. Lanthanide ion is used in experimental biology as a calcium antagonist; lanthanum oxide improves the optical properties of glass.
D008081	Liposomes	Artificial, single or multilaminar vesicles (made from lecithins or other lipids) that are used for the delivery of a variety of biological molecules or molecular complexes to cells, for example, drug delivery and gene transfer. They are also used to study membranes and membrane proteins.	Niosomes,Transferosomes,Ultradeformable Liposomes,Liposomes, Ultra-deformable,Liposome,Liposome, Ultra-deformable,Liposome, Ultradeformable,Liposomes, Ultra deformable,Liposomes, Ultradeformable,Niosome,Transferosome,Ultra-deformable Liposome,Ultra-deformable Liposomes,Ultradeformable Liposome
D008962	Models, Theoretical	Theoretical representations that simulate the behavior or activity of systems, processes, or phenomena. They include the use of mathematical equations, computers, and other electronic equipment.	Experimental Model,Experimental Models,Mathematical Model,Model, Experimental,Models (Theoretical),Models, Experimental,Models, Theoretic,Theoretical Study,Mathematical Models,Model (Theoretical),Model, Mathematical,Model, Theoretical,Models, Mathematical,Studies, Theoretical,Study, Theoretical,Theoretical Model,Theoretical Models,Theoretical Studies
D010713	Phosphatidylcholines	Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	Choline Phosphoglycerides,Choline Glycerophospholipids,Phosphatidyl Choline,Phosphatidyl Cholines,Phosphatidylcholine,Choline, Phosphatidyl,Cholines, Phosphatidyl,Glycerophospholipids, Choline,Phosphoglycerides, Choline
D000535	Aluminum	A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	Aluminium,Aluminium-27,Aluminum-27,Aluminium 27,Aluminum 27